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alanine丙氨酸手性分析HPLC
作者:nacalai
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丙氨酸
药物名称丙氨酸药物别名丙氨酸、α-氨基丙酸英文名称Alanine说 明功用作用用法用量注意事项作者:
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十一、实验动物血中游离氨基酸含量
...酸种类动物种类血标本种类氨基酸含量(毫克/100毫升)丙氨酸(Alanine)猫P7.0兔S1.7小白鼠P6.6(α-Aminobutyricdrid) 精氨酸(Arginine)狗P3.27±0.74猫P1.4兔S1.9大白鼠P3.21±0.58小白鼠P1.0门冬氨酸(Asparticacid)猫P0.1兔S<0.3胱氨酸、半胱氨酸(Cy...
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田七氨酸
...七氨酸[英文名称]Dencichine[别 名]Neurotoxin[化学名称]L-Alanine,3-[(carboxycarbonyl)amino]-[分子式]C5H8N2O5[分子量]176.13[物理性质]半水合物为无色结晶(50%乙醇),熔点164~167°[成分分类]氨基酸类[药理作用]具有止血作用。小鼠腹腔注射1mg...
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第五节 核苷酸的分解代谢
...氢胸腺嘧啶。二氢嘧啶酶催化嘧啶环水解,分别生成β-丙氨酸(β-alanine)和β-氨基异丁酸(β-aminosiobutyrate)。β-丙氨酸和β氨基异丁酸可继续分解代谢。β-氨基异丁酸亦可随尿排出体外。食入含DNA丰富的食物、经放射线治疗或...
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电堆积与等速电泳结合的毛细管电泳进样富集方法的研究
...电泳法进行了分离。pH4.0,30mmol/L醋酸钠-醋酸、30mmol/Lβ-丙氨酸-醋酸和1.5mmol/L醋酸钠-醋酸溶液分别作背景(或前导)、尾随和样品缓冲液。与常规电迁移进样方法比较,信号增强因子约为250和160;总分析时间与常规法相近。Abstra...
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实验室常用技术参数资料(三)
...酸名称三字母缩写单字母缩写质量侧链电离的pHa值结构式丙氨酸(alanine)AlaA89.09 精氨酸(arginine)ArgR174.212.48 天冬酰氨(asparagine)AsnN132.1 天冬氨酸(asparticacid)AspD133.13.86 半胱氨酸(systeine)CysC121.12 谷氨酰胺(glutamine...
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化学试剂知识介绍
...位。蛋白质经水解,即生成20多种α-氨基酸,如甘氨酸、丙氨酸、天冬氨酸、谷氨酸等。根据其结合基团不同。可分为脂肪族氨基酸、芳香族氨基酸、杂环氨基酸、含硫氨基酸、含碘氨基酸等,其理化特性大致有:1)都是无色结...
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Weightlossandelevatedgluconeogenesisfromalanineinlungcancerpatients
...ightlossinlungcancerisunclear.Objective:Ouraimwastostudygluconeogenesisfromalanineinlungcancerpatientsandtoanalyzeitsrelationtothedegreeofweightloss.Design:Inthiscross-sectionalstudy,weusedprimed-constantinfusionsof[6,6-2H2]-D-glucoseand[3-13C]-L-alaninetoassesswhole-bodyglucoseandalanineturnoverand...
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L-Argininesupplementationinpigsdecreasesliverproteinturnoverandincreaseshindquarterproteinturnoverbothduringandafterendotoxemia
...anintravenousinfusionofL-argininewasstarted(n=8).Controlpigs(n=6)receivedL-alanine.At24h,bloodwassampled.Aftercessationoftheendotoxininfusion,L-arginineandL-alanineinfusionswerecontinuedasasupplementintheenterallyinfuseddiet.At48h,bloodsampleswereobtainedduringthepostendotoxemicandnutritionallysuppo...
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眼咽肌型肌营养不良1例报告及文献复习
...分裂和有丝分裂期异常扩增了GCG三核苷酸。由于GCG编码为丙氨酸,导致PABPN1蛋白N端形成多个丙氨酸,在正常的(GCG)6上增加了2~7个GCG重复序列,因而成为(GCG)8~13,其中以(GCG)9的出现率为最多,且以具有(GCG)9重复序列患者...
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Inflammationcontributestolowplasmaaminoacidconcentrationsinpatientswithchronickidneydisease
...tedwithplasmaconcentrationsofasparagine,serine,glycine,citrulline,arginine,alanine,histidine,threonine,lysine,methionine,andtryptophanandwerealsonegativelycorrelatedwiththesumofNEAAconcentrations,thesumofEAAconcentrations,andthesumofallAAconcentrations[range:0.16(P0.05)to0.40(P0.0001)].I...
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蒋丽英:探索早期生命的奥秘
...。我们的主要研究是另一个化合物,BMAA(β-N-methylamino-L-alanine),这是一种和Parkinson,ALS等神经性疾病有关的二级氨基酸。它也产生于蓝绿藻,由于蓝绿藻在食物链中处于最底端,是很多生物特别是海洋生物的食物来源,所以BMA...
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第七章 氨基酸代谢--第一节 氨基酸的一般代谢
...酸和天冬氨酸: 或转给丙酮酸。生成α酮戊二酸和丙氨酸,通过第二次转氨反应,再生出α酮戊二酸。 因而体内有较强的谷草转氨酸(glutamicpyruvictransaminase,GPT)和谷丙转氨酸(glutamicoxaloacetictransaminase,GOT)活性。 转...
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2-AminoethoxydiphenylBorateDirectlyInhibitsChannelsComposedofConnexin26and/orConnexin32
...ro;M)bothinhibitheteromericCx26/Cx32hemichannels,buttheeffectsareadditive.-Alanine(10mM)reducestaurineinducedinhibitionbutnot2-APB-inducedinhibition.B,inhibition-concentrationrelationsfor2-APBaloneandwith10mM-alanineshowthatinhibitionby100µM2-APBisunchangedbycoapplicationwith-alanine.C,inhibit...
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中药标准品部分中英文对照
...alicinehydrochloride盐酸阿吗碱 Ajmaline阿吗灵 DLAlanineDL丙氨酸 LAlanineL丙氨酸 βAlanineβ丙氨酸 Aleuriticacid紫胶酮酸 Alginicacid藻酸 Alginicacidammoniumsalt藻酸铵盐 Alginicacidsodiumsalt藻酸钠盐 Alkannin紫草素 Ali...
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MetabolicandTherapeuticAspectsofAminoAcidsinClinicalNutrition,2nded,
...ersontheroleinnutritionandmetabolismofaminoacids,suchasglutamate,glutamine,alanine,andthebranched-chainaminoacids,whichhavebeenstudiedingreatdetailinrecentyears,andthetextincludesvaluableinformationontheroleofarginineinprovidingregulationofboththeureacycleandtheproductionofnitricoxide.Updatedinforma...
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实验室常用技术参数资料
...酸名称三字母缩写单字母缩写质量侧链电离的pHa值结构式丙氨酸(alanine)AlaA89.09 精氨酸(arginine)ArgR174.212.48 天冬酰氨(asparagine)AsnN132.1 天冬氨酸(asparticacid)AspD133.13.86 半胱氨酸(systeine)CysC121.12 谷氨酰胺(glutamine...
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WNKsignalinginthedistaltubule:aninhibitorycascaderegulatingsalttransport
...efectiveisoform.MolCellBiol23:92089221,2003.DowdBFandForbushB.PASK(proline-alanine-richSTE20-relatedkinase),aregulatorykinaseoftheNa-K-Clcotransporter(NKCC1).JBiolChem278:2734727353,2003.GagnonKB,EnglandR,andDelpireE.Volumesensitivityofcation-Clcotransportersismodulatedbytheinteractionoftwokinases:S...
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OCO在纺织领域中的应用
...胺酸(proline)12%、羟脯胺酸(hdroxyproline)10%,丙胺酸(alanine)有11%,羟离胺酸(hydroxylysine)0.5%。它是安全的生命构成物质。OCO的纳米活性、胶原生物活性和高效的皮肤渗透性是其优越于胶原蛋白、水解胶原、胶原肽、以及...
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DifferentialRegulationofHomocysteineTransportinVascularEndothelialandSmoothMuscleCells
...udiesrevealedthatthesmallneutralaminoacidstyrosine,cysteine,glycine,serine,alanine,methionine,andleucineinhibitedHcyuptakeinbothcelltypes,buttheinhibitionwasgreaterfortyrosine,serine,glycine,andalanineinHAECs.Sodium-depletionreducedHcytransportto16%inHAECsand56%inHASMCs.IncreasesinpHfrom6.5to8.2orly...
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RegulatoryphosphorylationsitesintheNH2terminusoftherenalNa-K-Clcotransporter(NKCC2)
...pstreamofthethreonineregulatorydomain,includingtherecentlyidentifiedprolinealanine-richSte-20-relatedkinase-bindingmotif.AchimericNKCCcontainingthefirst104aminoacidsofNKCC1ontheNKCC2backbonebehavedessentiallythesameasNKCC2,furtherarguingagainstamajorroleforthisupstreamregioninNKCC2regulation.renalso...
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Glutamine-enrichedenteralnutritioninvery-low-birth-weightinfantsandeffectsonfeedingtoleranceandinfectiousmorbidity:arandomizedcontrolledtrial
...n(0.3g·kg1·d1)orisonitrogenouscontrolsupplementation(alanine)betweendays3and30oflife.Thesupplementationswereaddedtobreastmilkortopretermformula.Theprimaryendpointforthestudywastimetofullenteralfeeding.Secondaryendpointswereothervariablesoffeedingtolerance,infectiousmorbidity,an...
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MethodsfortheDetectionofD-Amino-AcidOxidase
...f0.133Mpyrophosphatebuffer(pH8.3)containingcatalaseat700IU/ml,0.3mlof0.1MD-alanine,0.2mlof0.1mMFAD,and0.1mlof70%(V/V)methanol.Thereactionwasstartedbytheadditionof0.1mlofthesupernatantsolution.Thereactionwascarriedoutat37°Cfor15-60minutesdependingontheactivityofthesamples.Itwasterminatedbytheadditio...
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FirstInfectionwithVanD-TypeGlycopeptide-ResistantEnterococcusfaeciuminEurope
...ibitcellwallsynthesisthroughtheinteractionoftheirNterminiwiththeD-alanyl-D-alanineterminiofpeptidoglycanprecursors.Theresultingcomplexespreventthetransglycosylasesfromincorporatingdisaccharidepentapeptidesubunitsintothegrowingpeptidoglycanchain,therebyinhibitingcellwallsynthesis(15).Since1988,manyre...
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Vitreousamyloidosisinalanine71transthyretinmutation
...ptedforpublication20October2004Keywords:amyloidosis;transthyretin;mutation;alanineFamilialamyloidpolyneuropathy(FAP)associatedwithmutationsinthetransthyretin(TTR)geneisthecommonestformofhereditaryamyloidosis.TheincidenceofvitreousopacitiesinFAPvariesfrom5.4%to35%,1,2butvitreousopacitiesaspartofsyste...
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Aminoacidkineticsinpatientswithsepsis
...rves.Results:Withtheexceptionoflysine,methionine,glutamate,ornithine,phenylalanine,andtyrosine,plasmaconcentrationsofaminoacidswerelowerinthepatientswithsepsisthaninthecontrolsubjects;phenylalaninewastheonlyaminoacidwhoseplasmaconcentrationincreased(P0.001).Inpatientswithsepsis,whole-bodyclearance(C...
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ApolipoproteinBgenepolymorphismsandserumlipids:meta-analysisoftheroleofgeneticvariationinresponsivenesstodiet
...ndchangingthreoninetoisoleucine),anda3-codoninsertion-deletionpolymorphism(alanine-leucine-alanine)inthesignalpeptideregionofthehumanapoBgene.ThemethodsfordeterminingtheXbaIandEcoRIDNApolymorphismswerepublishedearlier(42).TheMspI,Bsp1261I,andsignalpeptidepolymorphismsweremeasuredbyusingspecificoligo...
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SuperoxideenhancesNa-K-2Clcotransporteractivityinthethickascendinglimb
...atedphysiologicalsalinecontaining(inmM)130NaCl,2.5NaH2PO4,4KCl,1.2MgSO4,6L-alanine,1Na2citrate,5.5glucose,2Cadilactate,and10HEPES(pH7.4).THALsweredissectedfromtheoutermedullaunderastereomicroscopeat10°Candtransferredtoatemperature-regulatedchamber,wheretheywereperfusedusingaconcentricglasspipetat37...
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TGF-β、c-myc与糖尿病肾病
...13ZiyadenFN,HanDC,CohenJA,etal.KidneyInt,1998,53:631. 14SinghR,AlaniN,SinghAK,etal.Diabetes,1999,48:2066. 15sharmak,ZiyadehFN.Diabets,1995,44:1139. 16wolfG,wuellerE,stahlRAK,etal.JClinInvest,1993,92:1366-1372. 17YoshidaH,kovV,IchikawaI.Polymorphismofreninangiotens...