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PreclinicalDiagnosisofAfricanSwineFeverinContact-ExposedSwinebyaReal-TimePCRAssay
...STRACTAfluorogenicprobehydrolysis(TaqMan)PCRassayforAfricanswinefevervirus(ASFV)wasdevelopedandevaluatedinexperimentallyinfectedswine.Thissensitiveandspecificone-stepsingle-tubeassay,whichcanbeperformedin2horless,detectedviralDNAintonsilscrapingsamples2to4dayspriortoonsetofclinicaldisease.Thus,theas...
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Humanintestinalmacrophagesdisplayprofoundinflammatoryanergydespiteavidphagocyticandbacteriocidalactivity
...recedencefordiscordantcytokineregulationisobservedinAfricanswinefevervirus(ASFV)inhibitionofmacrophageNF-BactivationthroughinductionofanIBhomologue,therebyinhibitingNF-B–dependentproductionofproinflammatorycytokinesbutnotTGF-?production;TGF-?mRNAandproteinareactuallyincreasedinASFV-infectedmacroph...
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四位科学家的转基因圆桌谈
...苏格兰的罗斯林研究所(RoslinInstitute)在做抗非洲猪瘟(ASFV)的转基因猪、抗非洲锥虫病(Africantrypanosomiasis)的牛,还有抗禽流感的鸡。还有人在做抗航运热(shippingfever)的牛,抗沙门氏菌的鸡……世界各地正在打着一场场战...