与Leser-Trélat征相关的文献报道

52例脂溢性角化病的临床与病理分析

...不难，偶有误诊为恶性黑色素瘤，但临床个别老年人出现Leser-Tre’lat征，提示恶性肿瘤存在的可能。本病病理上有某些特征及变异。我们对52例脂溢性角化病老年患者的临床与病理进行分析，现报告如下。　　1临床资料　　52例...

颈内动脉夹层致大面积脑梗死1例

...糖尿病、高脂血症等血管病危险因素。入院查体：生命体征平稳，心、肺、腹无异常发现。神经系统检查：昏睡状，理解力差，不能言语；右侧中枢性面瘫，右侧肢体肌力0级，左侧肢体肌力4级，右侧偏身痛觉减退，右下肢病理...

18F-FDGPET/CT显像对孤立性肺结节的诊断价值*

...部炎症及良性增殖性病变利用SUVmax、ΔSUV以及CT形态学特征综合分析也很难鉴别。【关键词】孤立性肺结节;脱氧葡萄糖;发射型计算机断层;SUV值　　[Abstract]ObjectiveToestimatethediagnosticaccuracyof18F-FDGPET/CTformalignantsolitarypulmonarynodules(SPN)....

NegativeRegulationofSuperoxideDismutase-1PromoterbyThyroidHormone

【关键词】NegativeRegulationTheroleofthyroidhormone[L-3,5,3‘-triiodothyronine(T3)]andthethyroidhormonereceptor(TR)inregulatinggrowth,development,andmetabolichomeostasisiswellestablished.ItisalsoemergingthatT3isassociatedwithoxidativestressthroughtheregulationoftheactivityofsuperoxidedismutase...

3D-FFE薄层双倍增强扫描在脑囊虫病定性诊断中的意义

...低于T1WI/SE增强扫描，对于病变的检出、头节检出及多环征的检出，3D-FFE/T1WI薄层增强扫描明显高于T1WI/SE增强扫描。结论3D-FFE薄层增强扫描，能大大提高囊虫检出率及定性诊断率，可作为脑囊虫病检查的常规序列。　　【关键词...

FunctionofBothSinusoidalandCanalicularTransportersControlstheConcentrationofOrganicAnionswithinHepatocytes

...词】FunctionWehypothesizedthatthefunctionofbothsinusoidalandcanaliculartransportersimportantlycontrolstheconcentrationsoforganicanionswithinnormalhepatocytes.Consequently,weinvestigatedhowacutetransportregulationofthesinusoidalorganicaniontransportingpolypeptides(Oatps)andthecanalicularmultidrugre...

ExcretionofLivingBorreliarecurrentisinFecesofInfectedHumanBodyLice

...sundercertainconditions.Inthe20thcentury,atleast7majorepidemicsoccurred.Thelatestlargeoutbreak(10millioncases)occurredduringandimmediatelyafterWorldWarII[1].AfterWorldWarII,theincidenceofLBRFdecreaseddramatically,disappearinginallareasexcepttheAndeanfoothillsandthehighlandsofcentralandeasternAfricam...

多囊卵巢综合征患者超排卵过程中行卵泡抽吸的效果观察

中华妇产科杂志2004Vol.39No.8P.522-525为了观察多囊卵巢综合征(PCOS)患者于行体外受精-胚胎移植(IVF-ET)的超排卵过程中抽吸卵泡的结局，广东学者对13例首次行IVF-ET(对照周期)失败、发生卵巢过度刺激征(OHSS)的PCOS不孕患者于再行IVF-ET(...

法国国家科学研究中心进行重组

...命新研究所的主任。CNRS将会进行提名，而政府会在全球征寻后进行任命。法国高等教育与研究部部长ValériePécresse表示，这一改组将会提高透明度并将“吸引到最优秀的科学家”。CNRS本计划与法国科技部及其他机构协商后于6月1...

外伤性膝关节骨梗死的MR表现

...走行长椭圆形3处。MR信号特点：9处病灶边缘表现为单环征，10处边缘表现为三环征，2处小病灶表现为灶性长T1、长T2信号。结论骨梗死MR表现特点明确，广泛应用可提高早期诊断率。【关键词】骨梗死；磁共振成像MRmanifestationoftra...

AdaptivehumanregulatoryTcells:mythorreality?

...néDescartesParis5,INSERMU580,H?pitalNecker-EnfantsMalades,Paris,France.AbstractItisnowwellestablishedthatadistinctsubsetofTlymphocytesisessentialfordownregulatingimmuneresponsestobothendogenous(self)andexogenousantigens.TheseTregsareCD4+andexpresshighlevelsofCD25(thechainoftheIL-2receptor)andthetra...

特异性抗人类白细胞抗原抗体的筛选与临床应用

...法　血清样本211份，采用微量酶联免疫法莱姆德抗原板(LAT)、混合抗原板(LATM)和补体依赖细胞毒(CDC)方法，随机双盲检测HLA抗体，比较其特异性与敏感性，分析3组肾移植受者的抗体水平。结果　所有样本的检测均获成功。LATM重复...

HumanadrenalglandssecretevitaminCinresponsetoadrenocorticotrophichormone

...takeisfromfoods,fastingplasmaconcentrationsdonotexceed80µmol/L.WepostulatedthatsuchtightcontrolpermitsaparacrinefunctionofvitaminC.Objective:ThepurposeofthisstudywastodeterminewhetherparacrinesecretionofvitaminCfromtheadrenalglandsoccurs.Design:Duringdiagnosticevaluationof26patientswithhyperald...

股骨头缺血性坏死的影像诊断评价与临床病例对照分析

...查，其中8例行MRI检查，18例行CT检查，且做了X线，CT与MRI征象的对照观察，并与同期临床和病例比较。结果30例经X线检查诊断ANFH者22例39髋，CT诊断ANFH者17例29髋，8例(包括8例X线片、CT检查阴性者)MRI检查均证实为ANFH16髋。统计表明...

LAT-mediatedsignalinginCD4+CD25+regulatoryTcelldevelopment

...diatedthroughthetransmembraneadaptorprotein,thelinkerforactivationofTcells(LAT).LATplaysanimportantroleinTcelldevelopment,activation,andhomeostasis.Aknock-inmutationatTyr136,whichisthephospholipaseC(PLC)-1–bindingsiteinLAT,leadstoasevereautoimmunediseaseinmice.Inthisstudy,weshowthatCD4+CD25+Tregce...

TheNaturalCourseofChlamydiatrachomatisInfectioninAsymptomaticColombianWomen:A5-YearFollow-UpStudy

...InstitutoNacionaldeCancerología,Bogota,ColombiaThenaturalcourseofChlamydiatrachomatisinfectionanditsriskfactorswerestudiedinColombianwomenwithnormalcytologicalresults,duringa5-yearperiod.Eighty-twowomenwhowerefoundtobepositiveforC.trachomatisatthestartofthestudywerestudiedat6-monthintervals.Ateachv...

TypeIInterferonProductionIsProfoundlyandTransientlyImpairedinPrimaryHIV-1Infection

InstitutCochin,Départementd‘Immunologie,INSERMU,CentreNationaldelaRechercheScientifique,UMR,IFR,UniversitéParisVRenéDescartesFacultédeMédecine,IFR,UniversitéRenéDescartes,ParisINSERMU,CohortePRIMOAgenceNationaledeRecherchecontreleSida,ServicedeMédecineInterne,HpitaldeBicêtreUnitéINSERME,...

《技术评论》09年度世界顶尖青年创新家揭晓

...nologyReview）杂志每年都会进行青年创新家的评选活动——TR35。评选领域包括医药、计算机、通讯、电子及纳米技术等，35位入选者年龄均在35岁以下，其研究成果正在改变我们的世界。日前，2009年度的TR35出炉。本年度35位入选者...

AmanwhohasmadehisMarksonscience

AscientificsymposiumhonoringthecontributionofPaulA.MarkstoscienceinNewYorkCitywasheldatColumbiaUniversityMedicalCenterinearlySeptember.BothColumbiaUniversityandMemorialSloan-KetteringCancerCenter(MSKCC)sponsoredthesymposium,whichhonoredthemanwho,asvicepresidentformedicalsciencesatColumbiaUniversityf...

ApoA-V

...tructuralanalyseshaveindicatedthatapoA-Vhasamulti-domainorganizationandisrelativelyhydrophobic/amphipatic.2Seepage1186ApoA-Visinvolvedintheregulationofplasmatriglyceridelevels.Thus,humanapoA-Vtransgenicmicehavelowertriglyceridelevelsthancontrols,whereastheknockoutshaveincreasedlevels.1Becausehypertr...

扩散张量纤维束成像对非脑回性皮层发育不良脑内主要纤维结构分析

...质纤维进行研究，旨在揭示该病脑内重要纤维结构改变特征，为临床预后评估提供功能解剖学依据。方法用SIEMENSTrio2003T对患者行全脑常规检查和扩散张量成像，然后进行数据收集和后处理。结果常规MRI左侧大脑半球体积增大，...

原发性输卵管癌的声像图表现

...肿物，记录肿物的大小、形态、与周围组织关系及血流特征。2结果　　原发输卵管癌6例，超声检查结果，肿瘤最大78cm×78cm，最小28cm×14cm，平均48cm，超声检查6例均有盆腔肿物，以囊性为主2例，以实性低回声...

RegulationofHumanApoA-IbyGemfibrozilandFenofibrateThroughSelectivePeroxisomeProliferator-ActivatedReceptorModulation

...,France.E-mailhelene.duez@pasteur-lille.frorbart.staels@pasteur-lille.frAbstractObjective—Theobjectiveofthistrialwastostudytheeffectsoffenofibrate(FF)andgemfibrozil(GF),themostcommonlyusedfibrates,onhigh-densitylipoprotein(HDL)andapolipoprotein(apo)A-I.MethodsandResults—Inahead-to-headdouble-bli...

胆管囊肿的磁共振诊断（附13例报告）

...缺损，紧贴底部胆管壁的的新月形充盈缺损表现为“新月征”，为少量泥沙沉积所致，本组3例均为手术证实。冠状位扫描有利于显示囊肿与胆管树的解剖关系。胆总管囊肿多表现为肝外胆管的囊状或梭状扩张，肝内胆管轻度扩...

ChemicalSynthesisofMT1andMT7MuscarinicToxins:CriticalRoleofArg-34inTheirInteractionwithM1MuscarinicReceptor

...artementd‘Ingénierieetd‘EtudedesProtéines,Gif-sur-Yvette,France：AbstractTopAbstractIntroductionMaterialsandMethodsResultsDiscussionReferencesTwomuscarinictoxins,MT1andMT7,wereobtainedbyone-stepsolid-phasesynthesisusingthe9-fluorenylmethoxycarbonyl-basedmethod.Thesyntheticandnaturaltoxins,iso...

MutationofthephospholipaseC-1–bindingsiteofLATaffectsbothpositiveandnegativethymocyteselection

...arch,FoodandDrugAdministration,Bethesda,MD20892LinkerforactivationofTcells(LAT)isascaffoldingadaptorproteinthatiscriticalforTcelldevelopmentandfunction.AmutationofLAT(Y136F)thatdisruptsphospholipaseC-1activationandsubsequentcalciuminfluxcausesapartialblockinTcelldevelopmentandleadstoaseverelymphopro...

EvaluationofAntimicrobialResistanceandTreatmentFailuresforChlamydiatrachomatis:AMeetingReport

CentersforDiseaseControlandPrevention,Atlanta,GeorgiaUniversityofWashington,SeattleLouisianaStateUniversityMedicalCenter,NewOrleansWorldHealthOrganization,Geneva,SwitzerlandEachyear,Chlamydiatrachomatiscauses3millionnewinfectionsandresultsinmorethan$1billioninmedicalcostsintheUnitedStates.Repeatorpe...

HSV-1能够长时间不被发现的分子机制

...会关闭自身的全部基因，只有一种名为潜伏—关联转录（LAT）的基因是个例外。科学家们在十多年前便已经找到了LAT，几年后，研究人员又发现，LAT的作用主要是通过抑制细胞凋亡从而防止被传染的细胞死亡，细胞凋亡是细胞自...

ApolipoproteinEPromotestheRegressionofAtherosclerosisIndependentlyofLoweringPlasmaCholesterolLevels

...H.W.),UniversityofCalifornia,SanFrancisco,andtheSanFranciscoVeteransAdministrationMedicalResearchCenter(R.L.R.);andtheGladstoneInstitutesofCardiovascularDiseaseandNeurologicalDisease(R.L.R.,S.M.L.,K.H.W.),SanFrancisco,California.CorrespondencetoRobertL.Raffai,PhD,DivisionofVascularSurgery,Department...

ProteinCharacterizationofNa-IndependentSystemLAminoAcidTransporterinMice

...】WerecentlyclonedthehumanNa-independentsystemLneutralaminoacidtransporterLAT3.TheaimofthepresentstudywastocharacterizethemolecularnatureofmouseLAT3attheproteinlevel.IsolatedmouseLAT3showed83%identitytohumanLAT3.XenopusoocytesinjectedwithmouseLAT3cRNAshowedthesamefunctionalpropertyashumanLAT3.Rever...