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RAGEExpressioninRhabdomyosarcomaCellsResultsinMyogenicDifferentiationandReducedProliferationMigrationInvasivenessandTumorGrowth
...dmyogenesis,increasedproliferation,andtumorformationinvivo.WeshowherethatTE671rhabdomyosarcomacells,whichdonotexpressRAGE,canbeinducedtodifferentiateontransfectionwithRAGE(TE671/RAGEcells)butnotasignaling-deficientRAGEmutant(RAGEcyto)(TE671/RAGEcytocells)viaactivationofaCdc42-Rac1-MKK6-p38pathwayand...
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StructuralFeaturesoftheGlutamateBindingSiteinRecombinantNR1/NR2AN-Methyl-D-aspartateReceptorsDeterminedbySite-DirectedMutagenesisandMolecular
...tebindingtoGluR2.The-carboxylinteractswiththehydroxylgroupsfromSer670andThr671,withadditionalsupportfromtheThr671backbonenitrogen(ArmstrongandGouaux,2000).AsisthecasewithTyr450intheGluR2subunit,His466,althoughnotparticipatingdirectlyinhydrogenbondingwithglutamate,seemstosealoffthepocketfromseveralwe...
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Skeletalmusclefatoxidation:timingandflexibilityareeverything
...seuptakeandcarbondioxideandlactateproductionintheforearm.J.Clin.Invest.35::671-682.Kelley,D.,andMandarino,L.2000..Fuelselectioninhumanskeletalmuscleininsulinresistance:areexamination.Diabetes.49::677-683.Storlien,L.,Oakes,N.,andKelley,D.2004..Metabolicflexibility.Proc.Nutr.Soc.63::363-368.Ukropcova,...
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径向基函数神经网络用于重叠色谱峰解析
...yan,CAIWen-sheng,etal.ChineseJournalofAnalyticalChemistry,1997,25(6):671-674邵学广,孙培艳,蔡文生,等.分析化学,1997,25(6):671-674[6]FANGJian-xing,WUMao-cheng,WANGDing-xing.SpectroscopyandSpectralAnalysis,1998,18(6):666-668方建兴,吴茂成,王定兴.光谱学与...
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校档案室采取多种方式提供查阅档案服务
...创新服务活动。2006年校档案室共提供利用档案4079卷次、671人次,其中提供电话代查达占总查档量的40%;复印、传真、e-mail达3055页,比2005年增加11%。档案室的这些新举措,提高了工作效率,同时促进了各部门档案归档率的提高...
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ProtectionfromAlzheimer‘s-likediseaseinthemousebygeneticablationofinduciblenitricoxidesynthase
...undwerecriticaltoavoidprematuremortalityinC57BL/6micebearingamutant(K670N,M671L)humanAPP(hAPP)transgene(27).WebredtheiNOS–/–C57BL/6xSJLmicewithastraincalledTg2576,inwhichahamsterprionpromoterdrivestheK670N,M671LAPPtransgeneintheC57Bl/6xSJLbackground(28),andwithtransgenicsinwhichtheThy1promoterdr...
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VANQWISH研究
...rate,influencedby:Procedure(PTCAvs.CABG)HospitalPatientpopulation100$2,353,671CostAnalysis-Invasivevs.Conservative(usingTIMIIIIBasamodel)ContiCR.ClinCardiol1995;18:187-188Invasivestrategy$1696perpatientaddedcost(1.5%lowerrateofdeathorMIby1year)作者:佚名
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BrothMicrodilutionSusceptibilityTestingofBrucellaSpecies:QualityControlLimitsforTenAntimicrobialAgentsagainstThreeStandardQualityControlStr
...ixantimicrobialregimensinthetreatmentofhumanbrucellosis.Clin.Infect.Dis.16:671-676.Mortensen,J.E.,D.G.Moore,J.E.Clarridge,andE.J.Young.1986.AntimicrobialsusceptibilityofclinicalisolatesofBrucella.Diagn.Microbiol.Infect.Dis.5:163-169.NationalCommitteeforClinicalLaboratoryStandards.2003.Methodsfordilu...
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Comparingthequalityofindicatorsofnutritionalstatusbyreceiveroperatingcharacteristicanalysisorbystandardizeddifferences
...ninterventions:theriskorthedifferential-benefitapproach?AmJClinNutr1996;63:6717.ErdreichL,LeeET.Useofrelativeoperatingcharacteristicanalysesinepidemiology.AmJEpidemiol1981;114:64962.HabichtJ-P.Somecharacteristicsofindicatorsofnutritionalstatusforuseinscreeningandsurveillance.AmJClinNutr1...
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第十章 练习题
...值比较患者2.603.243.733.734.325.185.585.786.406.53 健康人1.671.981.982.332.342.503.603.734.144.174.574.825.78 3.在研究人参镇镇静作用的实验中,曾有人以5%人参浸液对某批小白鼠20只作腹腔注射,而以等量蒸馏水对同批12只小白鼠作同样...
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pH标准缓冲溶液
...钾[KH3(C2O4)2#8226;2H2O]溶于无二氧化碳的水中,稀释至1000ml1.671.671.671.671.681.681.691.691.69不同温度时的pH值(pHindifferenttemperatures)45℃50℃55℃60℃70℃80℃90℃95℃-1.701.711.721.721.741.771.791.81-酒石酸盐标准缓冲溶液在25℃时,用无二氧化碳的...
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动脉粥样硬化性脑梗死患者载脂蛋白B基因多态性与血脂水平分析
...09±0.23##0.34±0.32#15X-X+5.20±1.172.42±1.211.17±0.392.75±0.821.31±0.671.12±0.240.27±0.2775E+E+5.17±1.55#2.09±1.03###1.30±0.382.76±1.391.13±0.33#1.09±0.23###0.35±0.32#105.00±1.60###3.86±1.89##**1.10±0.332.70±1.430.96±0.37###1.09±0.280.22±0.21 ***P<0.001,**P<0.02compare...
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Trackingtherecoveryofconsciousnessfromcoma
...ureysS.2003.Brain,consciousexperienceandtheobservingself.TrendsNeurosci.26:671–675.GusnardD.A.andRaichleM.E.2001.Searchingforabaseline:functionalimagingandtherestinghumanbrain.Nat.Rev.Neurosci.2:685–694.LaureysS.,OwenA.M.,SchiffN.D.2004.Brainfunctionincoma,vegetativestate,andrelateddisorders.Lan...
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附表8(1)F值表(1)-(4)(方差分析用)
....771.721.691.651251503.903.062.662.432.272.162.072.001.941.891.821.761.711.671.641502003.893.042.652.422.262.142.061.981.931.881.801.741.691.661.622003003.873.032.632.402.242.132.041.971.911.861.781.721.681.641.613005003.863.012.622.392.232.122.031.961.901.851.771.711.661.621.5950010003.853.002.612....
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AProspectiveObservationalStudyonTasteDisordersin102StrokePatients
...angCJ,HummelT.Neurologicalaspectsoftastedisorders.ArchNeurol.2003;60:667–671.WoschnaggH,StollbergerC,FinstererJ.Lossoftasteislossofweight.Lancet.2002;359:891.FinstererJ,StollbergerC,KopsaW.Weightreductionduetostroke-induceddysgeusia.EurNeurol.2004;51:47–49.Sanchez-JuanP,CombarrosO.Gustatorynervo...
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RoleintheSelectivityofNeonicotinoidsofInsect-SpecificBasicResiduesinLoopDoftheNicotinicAcetylcholineReceptorAgonistBindingSite
...attCD,andVecchiMP(1983)Optimizationbysimulatedannealing.Science(WashDC)220:671-680.[Abstract/FreeFullText]LansdellSJandMillarNS(2000)Theinfluenceofnicotinicreceptorsubunitcompositionuponagonist,-bungarotoxinandinsecticide(imidacloprid)bindingaffinity.Neuropharmacology39:671-679.[CrossRef][Medline]Le...
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Cachexiainchronickidneydisease:alinktodefectivecentralnervoussystemcontrolofappetite
...ndBaskin,D.G.2000..Centralnervoussystemcontroloffoodintake.Nature.404::661-671.Schwartz,M.W.,andMorton,G.J.2002..Keepinghungeratbay.Nature.418::595-597.Bruning,J.C.etal.2000..Roleofbraininsulinreceptorincontrolofbodyweightandreproduction.Science.289::2122-2125.Faggioni,R.,Feingold,K.R.,andGrunfeld,C...
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Bacterialtoxinsandtheimmunesystem:showmetheinvivotargets
...i.26:299–330.Mock,M.,andA.Fouet.2001.Anthrax.Annu.Rev.Microbiol.55:647–671.Hilleman,M.2004.Strategiesandmechanismsforhostandpathogensurvivalinacuteandpersistentviralinfections.Proc.Natl.Acad.Sci.USA.101:14560–14566.Früh,K.,K.Ahn,andP.A.Peterson.1997.InhibitonofMHCclassIantigenpresentationbyvi...
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SubtypeSpecificityofScorpion-ToxinTz1InteractionwithVoltage-GatedSodiumChannelsIsDeterminedbythePoreLoopofDomain3
...terizationofanovel-toxinfromtheVenezuelanscorpion,Tityuszulianus.Toxicon43:671-684.【参考文献】BorgesA,AlfonzoMJ,GarciaCC,WinandNJ,LeipoldE,andHeinemannSH(2004)Isolation,molecularcloningandfunctionalcharacterizationofanovel-toxinfromtheVenezuelanscorpion,Tityuszulianus.Toxicon43:671-684.Bosman...
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LackofEffectofPravastatinonCerebralBloodFloworParenchymalVolumeLossinElderlyatRiskforVascularDisease
...-contrastMRimaging:basicfactsandimplementation.Radiographics.2002;22:651–671.vanderFlierWM,MiddelkoopHA,Weverling-RijnsburgerAW,AdBehloulF,SpiltA,BollenELEM,WestendorpRGJ,vanBuchemMA.Interactionofmedialtemporallobeatrophyandwhitematterhyperintensities.Neurology.2004;25:1862–1864.PaulsonOB,Strand...
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DetectionofMethicillin-ResistantStaphylococcusaureus(MRSA)inBloodwiththeEVIGENEMRSADetectionKit
...hylococcusaureusbacteremiabynestedpolymerasechainreaction.Ann.Surg.224:665-671.Lem,P.,J.Spielgelman,B.Toye,andK.Ramotar.2001.DirectdetectionofmecA,nucand16SrRNAgenesinBacT/Alertbloodculturebottles.Diagn.Microbiol.Infect.Dis.41:165-168.Louie,L.,J.Goodfellow,P.Mathieu,A.Glatt,M.Louie,andA.E.Simor.2002...
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SerumparaoxonaseactivityisdecreasedintheactivestageofBeh?et’sdisease
...eJS,HollandGN,WilhelmusKR,eds.Ocularinfectionandimmunity.StLouis,Mosby1996:671–72.NiwaY,MiyakeS,SakaneT,etal.Auto-oxidativedamageinBeh?et’sdisease-endothelialcelldamagefollowingtheelevatedoxygenradicalsgeneratedbystimulatedneutrophils.ClinExpImmunol1982;49:247–55.TaysiS,KocerI,MemiogullariR,et...
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ImprovementoftheSpecificityofanEnzyme-LinkedImmunosorbentAssayforDiagnosisofParacoccidioidomycosis
...relationshipswithclinicalformsofparacoccidioidomycosis.J.Clin.Microbiol.31:671-676.Camargo,Z.P.,andM.F.Franco.2000.Currentknowledgeonpathogenesisandimmunodiagnosisofparacoccidioidomycosis.Rev.Iberoam.Micol.17:41-48.Camargo,Z.P.,C.Unterkircher,S.P.Campoy,andL.R.Travassos.1988.ProductionofParacoccidio...
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ApolipoproteinEe4alleleaffectsriskofhyperhomocysteinemiaintheelderly
...essedandtHcy,CRP,andserumconcentrationsoffolateandvitaminB-12weremeasuredin671cognitivelyhealthysubjects(52%women;meanage:73y)fromanItalianpopulationbasedprospectivecohortstudy.Results:APOE4carrierswithouthighCRP[multivariate-adjustedoddsratio(OR):0.22;95%CI:0.08,0.59]hadalowerriskofhyperhomoc...
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ACC/AHAST段抬高心梗2004指南解读
...bleasfulltextorexecutiveversionsathttp://www.acc.orgAntmanetal.JACC2004;44:671-719.WritingCommitteeTaskForceMembersWritingCommitteeMembersElliottM.Antman,ChairDanielT.Anbe,PaulWayneArmstrong,EricR.Bates,LeeA.Green,MaryHand,JudithS.Hochman,HarlanM.Krumholz,FrederickG.Kuschner,GervasioA.Lamas,CharlesJ...
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InVitroActivitiesofAnidulafunginagainstMorethan2,500ClinicalIsolatesofCandidaspp.,Including315IsolatesResistanttoFluconazole
...latesfrom15studysites),Europe(668isolatesfrom32studysites),andNorthAmerica(671isolatesfrom28studysites)(Table1).Inaddition,acollectionof315isolatesofCandidaspp.previouslycharacterizedasresistanttofluconazole(MIC,64μg/ml)(15)wastestedinordertodeterminetheactivityofanidulafunginagainsttheseclinically...
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盐酸布桂嗪片
...波长处测定吸收度,按C17H24N2O.HCl的吸收系数(E1cm1%)为671计算出每片的溶出量。限度为标示量的70%,应符合规定。 其他 应符合片剂项下有关的各项规定(附录ⅠA)。鉴别 取本品的细粉适量(约相当于盐酸布桂利...
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Catch-upgrowthinsmall-for-gestational-ageterminfants:arandomizedtrial
...M,StevenEM.Thesmall-for-dateinfant.1.Latergrowthpatterns.Pediatrics1972;49:67181.WaltherFJ.Growthanddevelopmentoftermdisproportionatesmall-for-gestationalageinfantsattheageof7years.EarlyHumDev1988;18:111.Hadders-AlgraM,TouwenBCL.Bodymeasurements,neurologicalandbehavioraldevelopmentinsix-...
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TACIandBAFF-RmediateisotypeswitchinginBcells
...ementforTRAF3insignalingbyLMP1butnotCD40inBlymphocytes.J.Exp.Med.199:661–671.Xu,S.,andK.P.Lam.2001.B-cellmaturationprotein,whichbindsthetumornecrosisfactorfamilymembersBAFFandAPRIL,isdispensableforhumoralimmuneresponses.Mol.Cell.Biol.21:4067–4074.Yan,M.,H.Wang,B.Chan,M.Roose-Girma,S.Erickson,T.B...
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Lowserumconcentrationsof25-hydroxyvitaminDinolderpersonsandtheriskofnursinghomeadmission
...falw.vu.nl.Seecorrespondingeditorialonpage471.SeecorrespondingCMEexamonpage671.ABSTRACTBackground:TheprevalenceofvitaminDdeficiencyinnursinghomepatientsishigh.Objective:Weaimedtoascertainwhetherlowerserum25-hydroxyvitaminD[25(OH)D]concentrationsincreasetheriskoffuturenursinghomeadmissionandearlydeat...