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动态比浊法定量检测复方氨基酸注射液(3AA)中的细菌内毒素
...号030610,规格10EU/支,厦门鲎试剂厂);复方氨基酸注射(3AA)批号200304012,200304121,200305093,200305161,200306222,规格250ml/瓶,湖北峰江);BET-32型细菌内毒素测定仪(天津大学无线电厂);ZH-2自动漩涡混合器(天津药典标准仪...
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动态比浊法定量检测复方氨基酸注射液(3AA)中的细菌内毒素
...号030610,规格10EU/支,厦门鲎试剂厂);复方氨基酸注射(3AA)批号200304012,200304121,200305093,200305161,200306222,规格250ml/瓶,湖北峰江);BET32型细菌内毒素测定仪(天津大学无线电厂);ZH2自动漩涡混合器(天津药典标...
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动态比浊法定量检测复方氨基酸注射液中的细菌内毒素
...030610,规格10EU/支,厦门鲎试剂厂);复方氨基酸注射液(3AA)批号200304012,200304121,200305093,200305161,200306222,规格250ml/瓶,湖北峰江);BET32型细菌内毒素测定仪(天津大学无线电厂);ZH2自动漩涡混合器(天津药典标...
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动态比浊法定量检测复方氨基酸注射液中的细菌内毒素
...030610,规格10EU/支,厦门鲎试剂厂);复方氨基酸注射液(3AA)批号200304012,200304121,200305093,200305161,200306222,规格250ml/瓶,湖北峰江);BET32型细菌内毒素测定仪(天津大学无线电厂);ZH2自动漩涡混合器(天津药典标...
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InvolvementofFoxotranscriptionfactorsinangiogenesisandpostnatalneovascularization
...llsandpostnatalvesselformationhasnotbeenstudied.Here,weshowthatFoxo1andFoxo3aarethemostabundantFoxoisoformsinmatureendothelialcellsandthatoverexpressionofconstitutivelyactiveFoxo1orFoxo3a,butnotFoxo4,significantlyinhibitsendothelialcellmigrationandtubeformationinvitro.SilencingofeitherFoxo1orFoxo3ag...
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异土木香内酯Isoalantolactone
...an-2(3H)-one,decahydro-8a-methyl-3,5-bis(methylene)-,(3aR-(3aa,4aa,8aB,9aa))-[分子式][分子量]232.31[物理性质]棱柱形结晶(稀乙醇),熔点112℃(115℃),溶于乙醇、乙醚、苯和氯仿,微溶于石油英,不溶于水。[成分分类][药...
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五梭决明素QuinquangulinHelenalin
...7a,8,9,9a-octahydro-4-hydroxy-4a,8-dimethyl-3-methylene-,(3aS-(3aa,4a,4aB,7aa,8a,9aa))-[分子式][分子量]262.29[物理性质]苦味结晶(苯),熔点167~168℃,(a)25D一102.8°(C=3.64,95%乙醇)。略溶于水,溶于乙醇、氯仿及热苯。[...
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乙型肝炎病毒X基因准种特点的研究
...变的突变可分为3类,一类是内部缺失突变,缺失长度自3aa(849-C3)至7aa(645-C2、32-2)不等,其羧基端结尾与正常形式相同;一类是缺失突变结合移框突变,X蛋白长度自133aa至152aa不等,羧基端多以TRRL或KV结束;另一类是移框突变造成...
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远程医疗对降低医疗条件薄弱地区患者心血管危险的作用
...menAA’shavea40%greaterprevalenceofhypertensioncomparedtowhites.Roughly1in3AA’shashypertension.AA’shavea?rateofmultipleriskfactors.ImplicationsAfrican-AmericanhaveahighprevalenceofCVDriskfactors.Theseriskfactorscanbeeffectivetreatedwithcurrentmedicaltherapy.Suboptimalcontrolofriskfactorscontrib...
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芍药甙Paeoniflorin
...-1H-3,4-dioxacyclobuta(cd)pentalen-la(2H)yl,{laR-(laa、2B,3aa,5a,5aa,5ba)}-[分子式][分子量]480.45[物理性质]吸湿性无定形粉末,(a)16D一12.8°(C=4.6,甲醇),四醋酸酯为无色针状结晶,熔点196℃。[成分分类][药理作用]1....
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关于征求阿糖腺苷等药品国家标准(草案)意见的函
...0复方含糖胃蛋白酶颗粒(消食灵颗粒)11复方亮氨酸颗粒3AA(肝安颗粒)12复方胃蛋白酶散(小儿消化止泻散)13复方胃膜素胶囊(胃疡宁胶囊)14复方胰酶散(胖得生)15复方紫龙片(咳喘片)16复合磷酸酯酶17复合磷酸酯酶肠溶...
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新型脊柱外固定器在胸腰椎爆裂性骨折临床应用中的适应证探讨
...图2脊柱外固定器体外配件工作原理示意图(略) 图3aA型骨折(略) 图3bB型骨折,(略) 图3cC型骨折(略) 图3dD型骨折(略) 表1不同类型骨折术前与术后的神经功能对比(略) 5.2新型脊柱外固定器应用...
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血管紧张素II受体-1基因A1166C多态性与双氢克尿噻降压疗效的相关性研究
...基因型患者的比较差异有显著性(P0.05),见表3。 表3AA、AC两组基因型患者治疗后收缩压、舒张压下降水平变化(略) 注:组间比较※P0.05 3讨论 EH是一种由遗传因素和环境因素共同作用引起的多基因遗传病,尽管...
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含马兜铃酸成分中药与尿路上皮恶性肿瘤
...移行细胞癌,至16周时全部大鼠均发生移行细胞癌。 3AA的致癌机制目前国内外的研究 结果显示AA的致癌机制是AA在体内形成AADNA加合物,后通过AADNA加合物使原癌基因ras基因发生AT颠换突变而活化,以及抑癌基因P53基...
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1-AntichymotrypsinGene(SERPINA3)A/TPolymorphismasaRiskFactorforAneurysmalSubarachnoidHemorrhage
...erentperipheralinflammatoryconditions,whichmayinfluencethefunctionofSERPINA3AA,AT,andTTproteins.18BecauseseveralotherpolymorphismsofSERPINA3genehavebeenfound(ie,promoterG/T,codon76,codon227,codon241,codon250,codon324,intron4,and3‘untranslatedregion),itisalsopossiblethatthenonrandomcombinationofris...
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异体脱蛋白松质骨复合纤维蛋白BMP修复兔桡骨缺损
...髓腔未完全形成图2e术后16周骨性链接形成,髓腔再通图3aA组术后16周大体图片,可见骨缺损已骨性愈合图3bB组术后16周大体图片,可见骨缺损有少量骨性连接,骨皮质不连续,尚有05cm缺损图3cC组术后16周大体图片,骨折缺损未愈...
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绿茶多酚保存同种异体神经移植体的实验研究
...后6周组织学观察,神经移植体中段,马森染色,×400图3aA组有较多新生轴突已长入移植体,排列整齐,神经纤维肿胀不明显图3bB组大量的空泡变性,大量纤维组织增生,再生神经纤维较少,且神经排列紊乱图3cC组神经移植物中...
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AmongBcellnon-Hodgkin‘slymphomas,MALTlymphomasexpressauniqueantibodyrepertoirewithfrequentrheumatoidfactorreactivity
...mparedtheIgVH-CDR3aminoacid(aa)sequencesofourpanelofMALTlymphomastoIgVH-CDR3aasequencespresentonGenBankusingtheNCBIProtein-BLASTprogramwiththeoption“searchforshortnearlyexactmatches“(BLASTP2.2.6;reference37).CDR3regionsconsistingofatleast7aa(allexceptM20)wereanalyzed(TableIV).ACDR3sequencewascon...
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GenotypeDistributionandMolecularEpidemiologyofHepatitisCVirusinBloodDonorsfromSoutheastFrance
...istributionwasobserved,withapredominanceofsubtype1a(40%),followedbysubtypes3aand1b(30%each).Overthe12-yearstudyperiod,genotypes1aand3aemergedwhilegenotypes1band2regressed.Toourknowledge,thisisthefirststudywhichhasanalyzedtheevolutionoftheHCVsubtypedistributionasafunctionoftheyearofbloodcollection.To...
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ComplementC3aandC4aIncreasedinPlasmaofPatientswithAspirin-inducedAsthma
...entcomponentlevelsinplasmawerevalidatedbyusingELISA.PlasmaconcentrationsofC3aandC4awerehigherinpatientswithAIA(n=30)thaninpatientswithATA(n=24).Aftertheaspirinchallenge,C3decreasedinbothpatientswithAIAandthosewithATA,buttheC3aconcentrationincreasedintheAIApatientgroup(p=0.019).Moreover,C3aandC4aleve...
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Alteredexpressionofjunctionaladhesionmolecule4ininjuredpodocytes
...stages.Inthesestages,JAM4stainingwasbroadlydetectedalongthecellsurface(Fig.3Aa).AttheS-shaped-bodystage,JAM4stainingwasdetectedonthepresumptivepodocytesandthepresumptiveproximaltubules(Fig.3Bb).IncontrasttoJAM4,MAGI-1stainingwasnotdetectedintherenalvesicleorthecomma-shapedbody.MAGI-1wasfirstdetected...
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SLC26A7:abasolateralCl-/HCO3-exchangerspecifictointercalatedcellsoftheoutermedullarycollectingduct
...dney.AsshowninFig.3A(lowermagnificationx40),SLC26A7isabsentinthecortex(Fig.3Aa)butisabundantintheoutermedulla(Fig.3Ab).TodeterminethespecificityoftheSLC26A7antibodyinratkidney,labelingintheoutermedullawasexaminedwiththepreadsorbedimmuneserum.Asindicated,preadsorbedserumdidnotdetectanylabelingintheou...
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Inhibitionofwild-typep66ShcAinmesangialcellspreventsglycooxidant-dependentFOXO3aregulationandpromotesthesurvivalphenotype
...andabsenceofN-acetylcysteine(NAC;50µM).ThephosphorylationstatusofFOXO3aanditssubcellularlocalizationarecriticalforitstranscriptionalactivity(26,35).ThesitesofFOXO3aphosphorylationbyAkt/PKBhavebeenmappedtothreekeyregulatoryresidues(35).Inoursystem,wetestedThr-32,asiteonFOXO3aknowntobephosphoryl...
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Insulin-LikeGrowthFactor-BindingProtein-InducesPulmonaryFibrosisandTriggersMononuclearCellularInfiltration
...wninFigure3A,onday8Tcellswerethepredominantcelltypeinthealveolararea(Figure3Aa).SomescatteredBcells(Figure3Ab)andseveralmonocytes/macrophages(Figure3Ac)werealsoobservedaroundthevesselsatday8afteradenoviraladministration.Atday14,thenumberofTcellsdecreased(Figure3,AdandB)(104.80??39.95/HPFversus22.65?...
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ClC-5:roleinendocytosisintheproximaltubule
...quantifiedbymeasurementoffluorescenceintensitynormalizedpercell.ShowninFig.3Aa,bothWTandKOprimaryproximaltubularcellstakeupsignificantquantitiesofalbumin(green),althoughtheamountinKOcellswasvisuallymuchlessthanthatinWTcells.NotethatcellsculturedfromtheMCDCalsotakeupalbuminbutthereisnoapparentdiffere...
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Thrombomodulin-ProteinC-EPCRSystem
...ingexplored,withrecognitionofitsabilitytoinactivatethepotentanaphylatoxinsC3aandC5a33andtheproinflammatorymediatorsbradykininandosteopontin.34Thrombomodulin:Structure–FunctionItisjust20yearsagothatEsmonandOwenidentifiedandisolatedTM.35,36Sincethattime,steadyprogresshasbeenmadeinelucidatingthemolec...
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AnandamideInhibitionof5-HT3AReceptorsVarieswithReceptorDensityandDesensitization
...2001a)Associationbetweenthe5‘UTRvariantC178ToftheserotoninreceptorgeneHTR3Aandbipolaraffectivedisorder.Pharmacogenetics11:471-475.[CrossRef][Medline]NieslerB,WeissB,FischerC,NothenMM,ProppingP,BondyB,RietschelM,MaierW,AlbusM,FranzekE,etal.(2001b)SerotoninreceptorgeneHTR3Avariantsinschizophrenicand...
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关于公布第二批化学药品说明书目录的通知
...(15)255.复方氨基酸注射液(17AA)256.复方氨基酸注射液(3AA)257.复方氨基酸注射液(9AA)258.复方氨基酸注射液(l5AA)259.复方氨基乙磺酸滴眼液260.复方倍他米松注射液261.复方苯硝那敏片262.复方薄荷脑注射液263.复方地舍平片264....
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LimitedProtectiveEffectoftheCCR532/CCR532GenotypeonHumanImmunodeficiencyVirusInfectionIncidenceinaCohortofPatientswithHemophiliaandSelect
...thanclone238).Thepatient-derivedThaiHIVisolate,BK132,divergedfrompatient1by3aa(positions7,11,and25)andusedtheCXCR4receptor[54].WearecurrentlysubstitutingtheV3loopofawell-characterizedHIVclonewiththepatient1derivedV3looptofunctionallytestthetissuetropismoftherecombinant(A.K.N.I.andB.Chesebro,unpublis...
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KineticsandregulationofaCa2+-activatedCl-conductanceinmouserenalinnermedullarycollectingductcells
...2+]iof10nM,noevidencefortheCaCCwasobtained,evenatlargepositivevoltages(Fig.3Aa).ThisdemonstratesthattheunderlyingCa2+-activatedCl-channelshaveanabsoluterequirementforintracellularCa2+toopen.Ata[Ca2+]iof100nM,wholecellcurrentswerealsoverysmall,butinaproportionofcells(6/13)slowoutwardcurrentrelaxation...