与（月扁）（piān）病相关的文献报道

（月扁）（piān）病

（月扁）（piān）病　　古病名。指患处赤脉卒起如编绳。且见有疼痛者。（月扁），脉隐起如辫绳也。（《集韵》）。《肘后备急方》卷五：“皮肉卒肿起，狭长赤痛名（月扁）。”该病多因久劳，或热气盛时为冷湿所折，致...

黄（王扁）

黄（王扁）　　明代医生。字楚祥。仪真（今江苏仪征）人。少丧父，从母习儒。既而思曰：“医，仁术也。苟精之，亦足以济世。穷研《素问》、《难经》等，医术益精，以医闻名于淮、扬间。正统初（1436年），征为太医，...

黄（王扁）

黄（王扁）　　明代医生。字楚祥。仪真（今江苏仪征）人。少丧父，从母习儒。既而思曰：“医，仁术也。苟精之，亦足以济世。穷研《素问》、《难经》等，医术益精，以医闻名于淮、扬间。正统初（1436年），征为太医，...

EmergencyAdministrationofAbciximabforTreatmentofPatientsWithAcuteIschemicStroke

...tPA.3RecurrentocclusionmightbesecondarytoprocoagulanteffectsofrtPA,andtherapiestocounteracttheseactionsareneeded.4Hence,thereisaneedforreperfusionagentsthatcouldbesafelyadministeredinalongertimewindow.Activationofplateletsisakeycomponentofacutethromboembolismandexperimentalstudiesalreadydemonstratet...

骈（pián）产

骈（pián）产　　骈，指并列或一对。骈产即双生。详该条。作者：

Regulationofphosphatidylinositol3–kinasebypolyisoprenylphosphatesinneutrophil-mediatedtissueinjury

...CenterofExperimentalTherapeuticsandReperfusionInjury,BrighamandWomen‘sHospitalandHarvardMedicalSchool,Boston,MA021152DepartmentofChemistry,UniversityofSouthernCalifornia,CA90089Neutrophilsplayacentralroleinhostdefense,inflammation,andtissueinjury.Recentfindingsindicateanovelroleforpolyisoprenylpho...

SafetyandEfficacyofMechanicalEmbolectomyinAcuteIschemicStroke

...ork,NYOregonHealthScienceUniversity(H.L.L.,G.M.N.),PortlandSaintLuke’sHospital(T.G.,M.M.R.),KansasCity,MoHartfordHospital(I.E.S.),Hartford,ConnDepartmentofRadiology(R.T.H.),UniversityofCalifornia,SanFranciscoRiversideMethodistHospital(R.F.B.),Columbus,OhiotheDepartmentofRadiology(M.P.M.),StanfordU...

Pioglitazonemitigatesrenalglomerularvascularchangesinhigh-fat,high-calorie-inducedtype2diabetesmellitus

...beingfedahigh-fat-caloriediet,andanincreaseinPPARactivitywasinducedbyaddingpioglitazone(Pi)tothediet.Miceweregroupedasfollows:normalcaloriediet(N),D,N+Pi,andD+Pi(n=6/group).Theglomerularfiltrationrate(GFR),renalarterybloodflowandpressure,andplasmaglucoseweremeasured.Renalglomeruliandpreglomerularart...

ProtectionfromangiotensinII–mediatedvasculotoxicandhypertensiveresponseinmicelackingPI3K

...el,Switzerland4DipartimentodiMedicinaSperimentaleePatologia,UniversitàLaSapienzadiRoma,00161Roma,ItalyHypertensionaffectsnearly20%ofthepopulationinWesterncountriesandstronglyincreasestheriskforcardiovasculardiseases.Inthepathogenesisofhypertension,thevasoactivepeptideoftherenin-angiotensinsystem,an...

抗逆转录病毒与骨量减少及骨质疏松的流行

...：HIV-阳性vsHIV-阴性；ART-治疗vsART-未治疗；蛋白酶抑制剂(PI)-治疗vsPI-未治疗，采用随机效应模型产生混合OR和置信区间。结果可见，在所有的37篇研究中，有20篇研究符合入选标准。在884例HIV感染患者中，67%出现BMD减低，其中15%患...

江浙沪地区汉族人群9个STR座位遗传多态性研究

...g平衡（P0.05）。其多态信息量（Polymorphisminformationcontent，PIC）均大于0.7201，杂合度（heterozygosity，H）均大于0.7296，个体识别力（powerofdiscrimination，DP）均大于0.7903，非父排除率（probabilityofpaternityexclusion，PE）均大于0.5306。随机个...

Phosphatidylinositol3,4,5-trisphosphate:anearlymediatorofinsulin-stimulatedsodiumtransportinA6cells

【摘要】InsulinstimulatessodiumtransportacrossA6epithelialcellmonolayers.Activationofphosphatidylinositol3-kinase(PI3-kinase)wassuggestedasanearlystepintheinsulin-stimulatedsodiumreabsorption(Ref.35).ToestablishthatthestimulationofthePI3-kinasesignalingcascadeiscausingstimulationofapicalepitheli...

Centralcontrolofrenalsodium-phosphate(NaPi-2)transporters

【摘要】Regulationofphosphate(Pi)reabsorptionoccursthroughtheup-anddownregulationoftherenaltype-IIsodiumPicotransporters(NaPi-2).Recently,renalNaPi2-typeexpressionhasbeenidentifiedinareasofthebrain.ThepresentstudydeterminedwhetherbrainNaPi-2isregulatedbydietaryPiandwhetherthebehavioralandrenalad...

LuminalflowinduceseNOSactivationandtranslocationintheratthickascendinglimb.II.RoleofPI3-kinaseandHsp9

...WefoundthataugmentingluminalflowinduceseNOSactivationandtranslocationtotheapicalmembraneofTHALs(OrtizPA,HongNJ,andGarvinJL.AmJPhysiolRenalPhysiol287:F274-F280,2004).Inothercells,eNOSactivationbyshearstressismediatedbyphosphatidylinositol3-OHkinase(PI3)-kinase.WehypothesizedthatluminalflowinduceseNOS...

CardiacSarcoplasmicReticulumCalciumReleaseandLoadAreEnhancedbySubcellularcAMPElevationsinPI3K-DeficientMice

...,Austria.AbstractWerecentlyshowedthatphosphoinositide-3-kinase-eCdeficient(PI3KeC/eC)micehaveincreasedcardiaccontractilitywithoutchangesinheartsizecomparedwithcontrolmice(ie,PI3K+/+orPI3K+/eC).Inthisstudy,weshowthatPI3KeC/eCcardiomyocyteshaveelevatedCa2+transientamplitudeswithabbreviateddecaykinetic...

Magnesiumrequirements:newestimationsformenandwomenbycross-sectionalstatisticalanalysesofmetabolicmagnesiumbalancedata

...qualtomagnesiumintake(M)]atmagnesiumintakesof165mg/d[95%predictioninterval(PI):113,237mg/d;Y=19.8+0.880M],2.36mg·kg–1·d–1(95%PI:1.58,3.38mg·kg–1·d–1;Y=0.306+0.870M),or0.075mg·kcal–1·d–1(95%PI:0.05,0.11mg·kcal–1·d–1;Y=0.0...

IntestinalNa-PicotransporteradaptationtodietaryPicontentinvitaminDreceptornullmice

...ntestinalNa+-dependentphosphatetransportadaptationtovariablelevelsofdietaryPi.Therefore,thegoalofthecurrentstudywastoassessNa+-dependentPicotransportactivityintransgenicmicetodeterminewhethervitaminDisanessentialmediatorofthisprocess.Intestinalbrush-bordermembrane(BBM),Na+-dependentPicotransportacti...

氨基酸分子的模糊聚类分析

【摘要】本文选用氨基酸分子的相对分子量、pI值、疏水性值以及保守性值这四个参数，利用模糊聚类的方法，对20种氨基酸分子进行了分类。通过对分类结果的分析，有助于我们研究蛋白质的相似性问题。【关键词】氨基酸；...

资深PI最新文章解析信号通路

来自新加坡分子与细胞生物学研究院，癌症与发育细胞生物学部的研究人员获得了YAP－TEAD4复合物在YAP因子N端结构域相互作用，以及在TEAD4C端结构域与YAP相互作用的晶体结构，从中研究人员认为YAP中的PXXΦP片段是与TEAD4相互作用...

PI3K-AktPathwaySuppressesCoagulationandInflammationinEndotoxemicMice

...issuefactor(TF).Inthisstudy,weanalyzedtheroleofthephosphoinositide3-kinase(PI3K)-Aktpathwayintheactivationofcoagulationandtheinnateimmuneresponseinamousemodelofendotoxemia.MethodsandResults—WortmanninandLY294002wereusedtoinhibitthePI3K-Aktpathway.WefoundthatwortmannininhibitedLPS-inducedAktphospho...

Adenovirus-MediatedIntraarterialDeliveryofPTENInhibitsNeointimalHyperplasia

...Durham,NC27710.E-mailcdkontos@duke.eduAbstractObjective—Phosphoinositide(PI)3-kinasepromotesvascularsmoothmusclecell(VSMC)responsesnecessaryforneointimalhyperplasia.Werecentlydemonstratedthattheinositol3-phosphatasePTENisexpressedinVSMCsandthatitsoverexpressioninhibitsthesecellularresponses.Thepur...

Inhibitionofphosphatidylinositol3-kinasestimulatesactivityofthesmall-conductanceKchannelintheCCD

...WeusedWesternblottingtoexaminetheexpressionofphosphatidylinositol3-kinase(PI3K)intherenalcortexandoutermedullaandemployedthepatch-clamptechniquetostudytheeffectofPI3KontheROMK-likesmall-conductanceK(SK)channelsinthecorticalcollectingduct(CCD).LowKintakeincreasedtheexpressionofthe110-kDa-subunit(p110...

纳洛酮对重型颅脑损伤脑血流动力学及颅内压的影响

...压监护仪监测颅内压。结果治疗组脑血流动力学Vs、Vm、PI值在纳洛酮治疗3天后与对照组相比明显改善（P＜0.05）；治疗组在第3天后平均颅内压明显低于对照组（P＜0.05）。结论大剂量纳洛酮能够改善重症颅脑损伤引起的脑血流动...

PredictorsofHIVDrug-ResistanceMutationsinaLargeAntiretroviral-NaiveCohortInitiatingTripleAntiretroviralTherapy

...ishColumbia,Canada.Methods.Allplasmasampleswithplasmavirusloads(pVLs)1000copies/mLcollectedduringthefirst30monthsoffollow-upweregenotypedfordrugresistance.Theprimaryoutcomemeasurewastimetothefirstdetectionofmajordrug-resistancemutation(s).Coxproportionalhazardregressionwasusedtoidentifyfactorssignif...

PI3Kintegratestheactionofinsulinandleptinonhypothalamicneurons

...shington,USA.AbstractCentralcontrolofenergybalancedependsontheabilityofproopiomelanocortin(POMC)oragouti-relatedprotein(Agrp)hypothalamicneuronstosenseandrespondtochangesinperipheralenergystores.Leptinandinsulinhavebeenimplicatedascirculatingindicatorsofadiposity,butitisnotclearhowchangesintheirleve...

蛋白质组鉴定技术

...Phospho或Fluoroimagers，对图象进行数字化.并成为以象素(pixels)为基础的空间和网格.其次，在图象灰度水平上过滤和变形，进行图象加工，以进行斑点检测.利用Laplacian，Gaussian，DOG(differenceofGaussians)opreator使有意义的区域与背景分...

蛋白质组鉴定技术

...Phospho或Fluoroimagers，对图象进行数字化.并成为以象素(pixels)为基础的空间和网格.其次，在图象灰度水平上过滤和变形，进行图象加工，以进行斑点检测.利用Laplacian，Gaussian，DOG(differenceofGaussians)opreator使有意义的区域与背景分...

蛋白质组鉴定技术

...Phospho或Fluoroimagers，对图象进行数字化.并成为以象素(pixels)为基础的空间和网格.其次，在图象灰度水平上过滤和变形，进行图象加工，以进行斑点检测.利用Laplacian，Gaussian，DOG(differenceofGaussians)opreator使有意义的区域与背景分...

PAR1,butNotPAR4,ActivatesHumanPlateletsthroughaGi/o/Phosphoinositide-3KinaseSignalingAxis

...wthatPAR1couplestoGi/oinhumanplateletsandactivatesphosphoinositide-3kinase(PI3K).PI3KactivationregulatesplateletintegrinIIb3activationandplateletaggregationandpotentiatesthePAR1-mediatedincreaseinintraplateletcalciumconcentration.PI3KinhibitorseliminatedtheseeffectsdownstreamofPAR1,buttheyhadnoeffec...

CilostazolProtectsAgainstBrainWhiteMatterDamageandCognitiveImpairmentinaRatModelofChronicCerebralHypoperfusion

...dimmunohistochemistryfor4-hydroxy-2-nonenal(HNE),glutathione-S-transferase-pi(GST-pi),ionizedcalcium-bindingadaptormolecule1,phosphorylatedCREB(p-CREB),Bcl-2,andcyclooxygenase-2(COX-2)wereanalyzedatbaselineandat3,7,14,21,and28daysafterhypoperfusion.Result—Cilostazolsignificantlyimprovedspatiallear...