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BreakthroughCandidakruseiFungemiaduringFluconazoleProphylaxisfollowedbyBreakthroughZygomycosisduringCaspofunginTherapyinaPatientwithSevereA
...ease:attentionrequired.Clin.Infect.Dis.40:e35-e37.Walsh,T.J.,R.W.Finberg,C.Arndt,J.Hiemenz,C.Schwartz,D.Bodensteiner,P.Pappas,N.Seibel,R.N.Greenberg,S.Dummer,M.Schuster,J.S.Holcenberg,etal.1999.LiposomalamphotericinBforempiricaltherapyinpatientswithpersistentfeverandneutropenia.N.Engl.J.Med.340:764-...
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AsymptomaticCarotidAtherosclerosisIsAssociatedWithCirculatingChlamydiapneumoniaeDNAinYoungerNormotensiveSubjectsinaGeneralPopulationSurvey
...edicalDepartment,Hanse-HospitalStralsund,TeachingHospitaloftheErnst-Moritz-Arndt-UniversityofGreifswald(R.M.,M.S.),InstituteofClinicalChemistryandLaboratoryMedicine(J.L.),DepartmentofNeurology(U.S.,C.K.),andInstituteofEpidemiologyandSocialMedicine(U.J.),Ernst-Moritz-Arndt-UniversityofGreifswald,Refe...
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CloseApproximationofTwoPlateletFactor4TetramersbyChargeNeutralizationFormstheAntigensRecognizedbyHITAntibodies
...o(grant#T-5207)andbytheDepartmentofCardiovascularMedicineoftheErnst-Moritz-Arndt-University-Greifswald.DeutscheForschungsgemeinschaftfundedtheworkonAFMimagingofnanosizedclustersandthedevelopmentofimageanalysistechniquesusedinthisstudyunderTR24.DisclosuresNone.【参考文献】ChongBH,PitneyWR,Casta...
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颅内静脉血栓的介入治疗
...osis.NeurolClin,1992,10(1):87-111. 2EinhauplKM,VillringerA,MeisterW,etal.Cerebralvenousthrombosis:nothing,heparin,orlocalthrombosis?Stroke,1999,30(3):481-483. 3KimberJ.Cerebralvenoussinusthrombosis.QJMed,2002,95(3);137-142. 4MslekAM,HigashidaRT.BalousekPA,etal.Endovasc...
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类风湿性关节炎早期40例诊断探讨
...可加拍斜位片[3]。本文所采集的40例患者均无明显不良反应和并发症,仅在注入造影剂后患者感到腕部胀痛,经1~2h随造影剂的吸收而可缓解。 2结果 平片:指间关节及腕关节肿胀37例(92.5%),骨质疏松36例(90%),关...
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Science:10个月数据述说“炙热故事”
...美国北卡罗来纳州国家气候数据中心气候监测部主任DerekArndt表示,今年一些月份(包括6月和10月)的空气平均气温刷新了全球纪录。“这些月份的异常现象打破了统计误差上限。”他说,“这非常不同寻常。”WMO的MichelJarraud在...
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RoleofEndocyticInhibitoryDrugsonInternalizationofAmyloidogenicLightChainsbyCardiacFibroblasts
...Endocytosis:whatgoesinandhow?JCellSci1992,103:1-8LidkeDS,NagyP,HeintzmannR,Arndt-JovinDJ,PostJN,GreccoHE,Jares-ErijmanEA,JovinTM:QuantumdotligandsprovidenewinsightsintoerbB/HERreceptor-mediatedsignaltransduction.NatBiotechnol2004,22:198-203BestermanJM,AirhartJA,LowRB,RannelsDE:Pinocytosisandintracel...
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SimpleMethodforDeterminationoftheNumberofHelicobacterpyloriCagAVariable-RegionEPIYATyrosinePhosphorylationMotifsbyPCR
...elialcells.Mol.Microbiol.42:631-644.Backert,S.,E.Ziska,V.Brinkmann,U.Zimny-Arndt,A.Fauconnier,P.R.Jungblut,M.Naumann,andT.F.Meyer.2000.TranslocationoftheHelicobacterpyloriCagAproteiningastricepithelialcellsbyatypeIVsecretionapparatus.Cell.Microbiol.2:155-164.Censini,S.,C.Lange,Z.Xiang,J.E.Crabtree,P...
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Possibleroleofhumanherpesvirus8inthelymphoproliferativedisordersincommonvariableimmunodeficiency
...ease.Br.J.Haematol.120:471–477.Albrecht,D.,T.Meyer,T.Lorenzen,A.Stoehr,R.Arndt,andA.Plettenberg.2004.EpidemiologyofHHV-8infectioninHIV-positivepatientswithandwithoutKaposisarcoma:diagnosticrelevanceofserologyandPCR.J.Clin.Virol.30:145–149.Hengge,U.R.,T.Ruzicka,S.K.Tyring,M.Stuschke,M.Roggendorf,...
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RecoveryofNa-glucosecotransportactivityafterrenalischemiaisimpairedinmicelackingvimentin
...C2.3.2.2)activitywasdeterminedusinganadaptationofthetechniqueofOrlowskiandMeister(29).Na-K-ATPase(EC3.6.1.3)activitywasdeterminedaccordingtothetechniqueofPostetal.(30).Specificitywasassessedusingouabain(8mM).BBMVTransportStudiesBBMVwereequilibratedfor60minatroomtemperatureinabuffercontaining300mMman...
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MRI对膝关节损伤的检查方法及诊断价值
...为较多的韧带纤维断裂,伴有部分功能丧失和较大的关节反应;Ⅲ度为韧带纤维的完全断裂或起止部撕脱,伴有明显的关节不稳。所有正常膝关节韧带在各种MRI序列中均表现为低信号,前交叉韧带(anteriorcruciateligment,ACL)是膝关节中最易...
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DevelopmentofaGeneral-Primer-PCR-Reverse-Line-BlottingSystemforDetectionofBetaandGammaCutaneousHumanPapillomaviruses
...averruciformisinchildrenwithpsoriasis.Br.J.Dermatol.149:819-825.Meyer,T.,R.Arndt,E.Christophers,I.Nindl,andE.Stockfleth.2001.Importanceofhumanpapillomavirusesforthedevelopmentofskincancer.CancerDetect.Prev.25:533-547.Munoz,N.,F.X.Bosch,S.deSanjose,R.Herrero,X.Castellsague,K.V.Shah,P.J.Snijders,andC....
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CouldHumanPapillomavirusesBeSpreadthroughBlood
...,SiHaandHeLacervicalcarcinomacelllines.J.Gen.Virol.80:1725-1733.Meyer,T.,R.Arndt,I.Nindl,C.Ulrich,E.Christophers,andE.Stockfleth.2003.Associationofhumanpapillomavirusinfectionswithcutaneoustumorsinimmunosuppressedpatients.Transplant.Int.16:146-153.Moscicki,A.B.,J.H.Ellenberg,S.Farhat,andJ.Xu.2004.Pe...
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Inhibitionofc-JunN-TerminalKinaseLimitsLipopolysaccharide-inducedPulmonaryNeutrophilInflux
...aseinlipopolysaccharide-stimulatedneutrophils.JClinInvest1999;103:851eC858.ArndtPG,SuzukiN,AvdiNJ,MalcolmKC,WorthenGS.Lipopolysaccharide-inducedc-JunNH2-terminalkinaseactivationinhumanneutrophils:roleofphosphatidylinositol3-kinaseandSyk-mediatedpathways.JBiolChem2004;279:10883eC10891.LewisA,DiCianoC...
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Subtype-SpecificAffinityforCorticosteroneofRatOrganicCationTransportersrOCT1andrOCT2DependsonThreeAminoAcidswithintheSubstrateBindingRegi
...e(ratOCT2),and5e(ratOCT3)(Gredemannetal.,1998;Wuetal.,1998;Zhangetal.,1998;Arndtetal.,2001;Hayer-Zillgenetal.,2002).WerecentlyreportedtheexpressionofratOCT2(rOCT2)inoocytesofXenopuslaevisandinvestigatedtheinhibitionofcation-inducedinwardlyandoutwardlydirectedcurrentsaftershort-termaddition(30s)ofcor...
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Proteasome-mediateddegradationofIBandprocessingofp105inCrohndiseaseandulcerativecolitis
...oU.SteinhoffandA.Kroesen)andSFB421(toU.Steinhoff).WethankP.Krienke,U.Zimny-Arndt,D.Oberbeck-Mueller,N.Slavova,S.Dullat,andM.SchmidfortechnicalsupportandU.KuckelkornandP.Kloetzelforhelpfuldiscussions.ReferencesBoumaG.andStroberW.2003.Theimmunologicalandgeneticbasisofinflammatoryboweldisease.Nat.Rev.I...
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DistinctDiversityofvacA,cagA,andcagEGenesofHelicobacterpyloriAssociatedwithPepticUlcerinJapan
...Japan.J.Clin.Microbiol.42:2508-2517.Backert,S.,E.Ziska,V.Brinkmann,U.Zimny-Arndt,A.Fauconnier,P.R.Jungblut,M.Naumann,andT.F.Meyer.2000.TranslocationoftheHelicobacterpyloriCagAproteiningastricepithelialcellsbyatypeIVsecretionapparatus.Cell.Microbiol.2:155-164.Backert,S.,S.Moese,M.Selbach,V.Brinkmann,...
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AssessingtheSerodiagnosticPotentialof35MycobacteriumtuberculosisProteinsandIdentificationofFourNovelSerologicalAntigens
...gn.Lab.Immunol.9:883-891.Jungblut,P.R.,U.E.Schaible,H.J.Mollenkopf,U.Zimny-Arndt,B.Raupach,J.Mattow,P.Halada,S.Lamer,K.Hagens,andS.H.Kaufmann.1999.ComparativeproteomeanalysisofMycobacteriumtuberculosisandMycobacteriumbovisBCGstrains:towardsfunctionalgenomicsofmicrobialpathogens.Mol.Microbiol.33:1103...
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ComparisonbetweentheHybridCaptureIITestandaPCR-BasedHumanPapillomavirusDetectionMethodforDiagnosisandPosttreatmentFollow-UpofCervicalIntr
...t.85:958-964.Schneede,P.,P.Hillemanns,F.Ziller,A.Hofstetter,E.Stockfleth,R.Arndt,andT.Meyer.2001.EvaluationofHPVtestingbyHybridCaptureIIforroutinegynaecologicscreening.ActaObstet.Gynecol.Scand.80:750-752.Sherman,M.E.,A.T.Lorincz,D.R.Scott,S.Wacholder,P.E.Castle,A.G.Glass,I.Mielzynska-Lohnas,B.B.Rush...
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HyaluronidaseExpressionInducesProstateTumorMetastasisinanOrthotopicMouseModel
...ingandendocytosis.Biochemistry1993,32:12039-12045LidkeDS,NagyP,HeintzmannR,Arndt-JovinDJ,PostJN,GreccoHE,Jares-ErijmanEA,JovinTM:QuantumdotligandsprovidenewinsightsintoerbB/HERreceptor-mediatedsignaltransduction.NatBiotechnol2004,22:198-203ZacharakisG,KambaraH,ShihH,RipollJ,GrimmJ,SaekiY,WeisslederR...
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GenomicApproachtoIdentificationofMycobacteriumbovisDiagnosticAntigensinCattle
...nfect.Immun.65:2321-2328.Jungblut,P.R.,U.E.Schaible,H.J.Mollenkopf,U.Zimny-Arndt,B.Raupach,J.Mattow,P.Halada,S.Lamer,K.Hagens,andS.H.Kaufmann.1999.ComparativeproteomeanalysisofMycobacteriumtuberculosisandMycobacteriumbovisBCGstrains:towardsfunctionalgenomicsofmicrobialpathogens.Mol.Microbiol.33:1103...
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关于发布《药品不良反应监测管理办法(试行)》的通知
...,国家药品监督管理局会同卫生部组织制定了《药品不良反应监测管理办法(试行)》(以下简称《办法》),现印发给你们,并将有关实施要求通知如下:一、《办法》的颁布,标志着我国药品不良反应报告制度实施的开始。...
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《药品不良反应报告和监测管理办法》(局令第7号)
... 国家食品药品监督管理局第7号 《药品不良反应报告和监测管理办法》经中华人民共和国卫生部、国家食品药品监督管理局审议通过,现以国家食品药品监督管理局局令顺序号发布。本办法自发布之日起施行。 ...
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关注药品不良反应
药品不良反应(adversedrugreaction,ADR),是指合格药品在正常用法、用量下出现的与用药目的无关的或意外的有害反应,主要包括副作用、毒性作用、后遗效应、过敏反应、继发反应、特异性遗传素质等。从药品不良反应的定义...
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关于征求对《药品不良反应监测管理办法(试行)》修改意见的通知
...、直辖市药品监督管理局,卫生厅(局):实施药品不良反应(下称ADR)报告制度是做好ADR监测工作的关键。自1999年11月国家药品监督管理局和卫生部制定下发《药品不良反应监测管理办法(试行)》(下称《试行办法》)以来...
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对药物不良反应监测报告制度落实情况的探讨
【关键词】药物不良反应监测报告制度对于药品不良反应监测报告制度的落实,对于一个临床药师来讲,长期以来是一个非常棘手的问题,每一个医疗机构专职做此项工作的人员(大多是临床药师)都有这样体会。通过笔者几年工...
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基层医院建立药物不良反应报告制度的探讨
【关键词】基层医院药物不良反应报告制度 药物治疗给许多病人解除病痛,带来健康,但同样药物不良反应也会给许多人造成药害,引起后遗症,甚至死亡。随着人们要求健康的水平提高,已不再满足有药可用,要求提高治...
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关于印发全国药品不良反应监测工作会议文件的通知
...直辖市药品监督管理局(医药局)、卫生厅(局),药品不良反应监测中心:2000年6月6日至7日,国家药品监督管理局和卫生部在湖北省武汉市联合召开了全国药品不良反应监测工作会议。除吉林、西藏外,全国29个省、自治区、直辖...
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不同智商儿童视觉与听觉反应时测定
【摘要】目的探讨儿童反应时与智商的关系及影响因素,为儿童智力开发及更好地开展儿童教育工作提供科学参考。方法用对比分析的方法对3组儿童进行智商及反应时测定。智商测试选用《瑞文测试联合型》(CRT)城市儿童常模,...
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药物合成反应(第二版)
...、烃化、酰化、缩合、重排、氧化和还原等单元有机合成反应的本质和应用,第八章为合成设计原理。为了突出药物合成中反应物的骨架、官能团或化学键变化的基本特征,各章内容均按不同官能团化合物的反应来列题编排,对...