艾滋病流行二十年后的今天和再二十年后的未来
...Load抑制低滴度时,再用其他间歇疗法如羟基脲(Hydroxyurea)+ddI,或者治疗性疫苗,或者中草药。我国也报告了中草药在艾滋病治疗的效果,如上海市雄琪Ⅱ号(XQ-9302)经过对HIVLoad的评估,在低度、中度HIV载量的情况下,其初步结果...
合作平台;医学论文;临床医学与专科论文;检验医学DNAMacrorestrictionAnalysisofNontypeableGroupBStreptococcalIsolates:ClonalEvolutionofNontypeableandTypeVIsolates
...nodetectableCPSisfound.Surface-localizedproteinantigens(,,R1,andR4)serveasadditionalmarkerstoclassifyGBSisolates,whichisparticularlyusefulsinceNTisolatesoftenexpressoneormoreoftheseproteins.Tocomparegeneticresemblanceamongisolateswithsimilarproteinprofiles,westudied58NTisolatesdigestedwiththeSmaImac...
医源资料库;在线期刊;微生物临床杂志;2005年第43卷第2期第四十章 临床药理学进展与二十一世纪药物治疗学展望
...物,标准给药剂量为每日400-500mg。另外,双脱氧肌苷(ddI)是在日本已得到承认的药物具有较好的临床效果。 十一、TDM和药代动力学的应用 实行个体化给药时,设定初始剂量并由此获得血药浓度再行高速用药量。群体...
医源资料库;医源图书馆;教材类;医院药学Moderatedietaryfatconsumptionasariskfactorforischemicheartdiseaseinapopulationwithalowfatintake:acase-controlstudyinKoreanmen
...ersityCollegeofMedicine,Seoul,RepublicofKorea;theDepartmentofEpidemiologyandDiseaseControl,GraduateSchoolofHealthScienceandManagement,YonseiUniversity,Seoul,RepublicofKorea;theDepartmentofMedicine,UniversityofWashington,Seattle;theDepartmentofPreventiveMedicine,CatholicUniversityCollegeofMedicine,Se...
医源资料库;在线期刊;美国临床营养学杂志;2001年73卷第4期Newreferencevaluesforthyroidvolumebyultrasoundiniodine-sufficientschoolchildren:aWorldHealthOrganization/NutritionforHealthandDevelopmentIo
...onswereroutinelydonewiththe4-cmtransducer;the6-cmtransducerwasusedonlywhenadditionallengthwasneededtocompletelymeasurethecranial-caudaldimensionofthethyroidonasingleimage.Measurementswereperformedwhilethesubjectssatuprightinastraight-backedchairwiththeirneckextended.Foreachthyroidlobe,themaximumperp...
医源资料库;在线期刊;美国临床营养学杂志;2004年79卷第2期Identificationofcellulardeoxyhypusinesynthaseasanoveltargetforantiretroviraltherapy
...mitochondrialtoxicity,lipodystrophy,diabetesmellitus,andosteoporosis(5).Inaddition,HIV-1canacquireresistancetoallknowninhibitorsofreversetranscriptase,protease,andgp41,andtransmissionofmultidrug-resistantHIVstrainsisbecomingagrowingproblemamongnewlyinfectedpersons.Infact,arecentstudyreportedthatthep...
医源资料库;在线期刊;临床研究杂志;2005年第115卷第1期PhysicalInactivityIncreasesOxidativeStress,EndothelialDysfunction,andAtherosclerosis
...nningcomparedwithsedentarybehavioronparametersofvascularoxidativestress.Inaddition,weusedthemodelofcholesterol-fedapolipoproteinE–deficient(apoE–/–)micetoexaminetheeffectsofinactivityversusrunningonendothelialfunctionandatheroscleroticlesionformation.MethodsTheMethodssectionisavailableintheonl...
医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2005年第25卷第4期Dietaryfishintakeandplasmaphospholipidn3polyunsaturatedfattyacidconcentrationsinmenandwomenintheEuropeanProspectiveInvestigationinto
...yprogramgrantsfromtheMedicalResearchCouncilUKandCancerResearchUKandthroughadditionalsupportfromtheEuropeanUnion,StrokeAssociation,BritishHeartFoundation,theDepartmentofHealth,theFoodStandardsAgency,andtheWellcomeTrust.3AddressreprintrequestsandcorrespondencetoAWelch,DepartmentofPublicHealthandPrimar...
医源资料库;在线期刊;美国临床营养学杂志;2006年84卷第6期多头并进探寻新路——2006年医药科研领域大事回顾(三)
...奈韦拉平(NVP)、3TC/叠氮胸苷(AZT)/NVP和AZT/去羟肌苷(DDI)/NVP中,经为期一年的国产药治疗和随访发现,患者病毒载量下降的水平、CD4+T细胞上升数量等与国际临床研究数据相比未见明显差异;58.8%的患者血浆中的病毒被抑...
医学教育;科教新闻ModelingtheInfluenceofAPOC3,APOE,andTNFPolymorphismsontheRiskofAntiretroviralTherapyAssociatedLipidDisorders
...sterolemiaandhypertriglyceridemia[4],whereasuseofstavudine(d4T),didanosine(ddI),and,insomestudies,PIsareassociatedwithlipoatrophy[2].However,thesecomplicationsdonotoccurinallpatients,despitesimilarexposuretoARTandcomparabledemographic,immunologic,andvirologiccharacteristics.Thereasonsforthisdiscrepa...
医源资料库;在线期刊;传染病学杂志;2005年第191卷第9期