第四节 继发性免疫缺陷病
...’-azidothymidine,AZT)、二脱氧肌苷(2’,3'-dideoxyinosine,ddI)和二脱氧胞苷(2’,3’-dideoxycytidine,ddC),均逆转录酶抑制剂。1985年AZT开始临床试用,能延长生存期,但不能完全抑制病情且毒性大。其原因在于:HIV基因组序列的...
医源资料库;医源图书馆;教材类;医学免疫学深圳市龙岗区小学生肥胖现况调查及对策
...dtothestatusoffatnessandoverweightinpupilsinLonggangDistrictandgoodlivinganddi-etaryhabitsbenourished. Keywords:Fatness;Overweight;Bodymassindex(BMI);Pupil 肥胖及由肥胖引起的一系列疾病如心血管疾病等是当前困扰人类的一大健康问题,特别是近年来儿...
医源资料库;在线期刊;中国热带医学杂志;2006年第6卷第5期抗逆转录酶耐药基因研究现状及检测手段进展
...分别是齐多夫定(Zi-dovudine,AZT)、地丹诺辛(Didanosine,ddI)、扎西他宾(Zal-citabine,ddc)、司他夫定(Stavudine,d4T)、阿巴卡韦(Abacavir,ABC)、拉米夫定(Lamivudine,3TC);非核苷类逆转录酶抑制剂有3种,分别是内韦拉平(Nevi...
合作平台;在线期刊;中华实用医药杂志;2004年第4卷第24期;综述急性等容血液稀释用于脊柱手术
...4:234-235. 5MichenfolderJD,TheyeRA.Theeffectsofprofoundhypothermiaanddi-lutionalanemiaoncaninecerebralmetabolismandbloodflow.Anesthe-siology,1969,31:449-457. 6FanFC,ChenRYZ,SchuesslerGB,etal.Effectsofhematocritvariationsonregionalhemodynamicsandoxygentransportinthedog.AmJPhysi-...
合作平台;在线期刊;中华医药杂志;2005年第5卷第7期;临床医学GeneticPolymorphismsinCX3CR1PredictHIV-1DiseaseProgressioninChildrenIndependentlyofCD4+LymphocyteCountandHIV-1RNALoad
...enotypedfor2CX3CR1polymorphisms,V/I249andT/M280,andtheirimpactonHIV-1relateddiseaseprogression,includingcentralnervoussystem(CNS)impairment,wasevaluated.Results.ChildrenwiththeCX3CR1I/I249genotypeexperiencedmore-rapiddiseaseprogression(I/I249vs.V/V249:relativehazard[RH],2.19[95%confidenceinterval{CI...
医源资料库;在线期刊;传染病学杂志;2005年第191卷第11期雷公藤多甙与DC单抗对小鼠自身免疫性甲状腺炎作用的研究
...104 2 AhmannAJ,BurmanKD.TheroleofTlymphocyteinautoimmunethyroiddisease.EndocrinolMetabClinNorthAm,1987,16:287 3 陶学濂,孙瑛,董怡,等.雷公藤多甙治疗类风湿关节炎的双盲研究.中华内科杂志,1987,26:399 4 潘志超,许化溪,刘...
合作平台;医学论文;临床医学与专科论文;检验医学MembranelocalizationandpH-dependenttransportofanewlyclonedorganiccationtransporter(PMAT)inkidneycells
...tedattheapicalmembranebythemultidrugresistanceproteinMDR1(ABCB1)(10,19).Inaddition,twonovelorganiccationtransportersOCTN1/2,whichalsobelongtotheSLC22family,havebeenfoundinthekidney.OCTN1and2arelocalizedtotheapicalmembranes,wheretheymayparticipateinapicaltransport(secretionorreabsorption)ofsomeorgani...
医源资料库;在线期刊;美国生理学杂志;2007年第290卷第2期置入双腔起搏心脏复律除颤器及经腋静脉送入心内电极的初步临床体会
...erdefibrillator.Theunderlyingdiseaseswerecoronaryarterydiseasein5patientsanddilatedcardiomyopathyin2patients.Theatrialandventricularleadswereintroducedviatheaxillaryveinundervenographicguidence.Results Thedualchamberpacemakerdefibrillatorsweresuccessfullyimplantedintheleftchestsubcutaneouspocketin...
合作平台;医学论文;外科论文;心脏外科学干扰素在治疗爱滋病相关综合征中的应用
...早批准用于治疗AIDS的药物,该类药物还包括双去氧肌苷(ddI)和双去氧胞苷(ddC)〔8〕。 Ⅰ期试验提示,干扰素和AZT联合用药的最大耐受量为α干扰素9×106IU/d,加AZT100mg,q4h〔5〕。Fischl〔9〕对56例患者进行联合治疗,结果发现有...
合作平台;医学论文;临床医学与专科论文;药学PrognosticValueofBaselineHumanImmunodeficiencyVirusType1DNAMeasurementforDiseaseProgressioninPatientsReceivingNucleosideTherapy
...phenotype;thesemeasurementswereassociatedwithHIVdiseaseprogression[7,8].Inaddition,DNAfromPBMC(storedfrozen)wasisolated,andHIV-1DNAlevelswerequantified.ThegoalofthepresentstudywastoevaluatetheassociationofbaselineHIV-1DNAlevelwithbaselineandfollow-up(weeks8,20,and56)levelsofplasmaHIV-1RNA,infectious...
医源资料库;在线期刊;传染病学杂志;2003年第187卷第1期