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The3‘-untranslatedregionoftheSte20-likekinaseSLKregulatesSLKexpression
【摘要】Ste20-likekinase,SLK,agerminalcenterkinasefoundinkidneyepithelialcells,signalstopromoteapoptosis.ExpressionofSLKmRNAandproteinandkinaseactivityareincreasedduringkidneydevelopmentandrecoveryfromischemicacuterenalfailure.The3‘-untranslatedregion(3‘-UTR)ofSLKmRNAcontainsmultipleadeninea...
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RenalexpressionandactivityofthegerminalcenterkinaseSK
...stentwithSK2,agroupIIgerminalcenterkinaseandhomologofhumanSte20-likekinase(SLK).SK2mRNA,proteinexpression,andkinaseactivitywereincreasedinratfetalkidneyhomogenates(embryonicdays17-21)comparedwithadultcontrols.Inadultkidneyssubjectedtocross-clampingoftherenalartery,followedbyreperfusion,SK2mRNA,prote...
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Autologousserumeyedropsforocularsurfacedisorders
...ersistentepithelialdefect;RES,recurrenterosionsyndrome;rpm,roundsperminute;SLK,superiorlimbalkeratoconjunctivitis;SOP,standardoperatingprocedures;TGF-?,transforminggrowthfactorbetaKeywords:serum;bloodproducts;ocularsurface;dryeye;persistentepithelialdefect;regulatoryrestrictionsEyedropsmadefromautol...
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GlycyrrhizicacidaltersKaposisarcoma–associatedherpesviruslatency,triggeringp53-mediatedapoptosisintransformedBlymphocytes
...werenosignificantdifferencesinthegrowthcurvesofallKSHV-negativecells(Ramos,SLK,HUVEC,keratinocytes,andBJAB),eitheruntreatedortreatedwith2,3,or4mMGA,andtheirproliferationrateswerecomparabletothatofuntreatedKSHV-infectedcells.Ontheotherhand,inthepresenceof4mMGA,thenumberofviableKSHV-infectedcellsdecre...
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干眼症研究进展的综述
...方球结膜较下方多见,被认为是上方角膜缘部角结膜炎(SLK)的一个原因。上泪小点封闭可有效地减少瞬目所造成的损伤,从而改善非暴露的眼表状况。 4.3抑制眼表炎症和免疫抑制治疗抗炎和免疫抑制治疗只适合于有眼表炎症...