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Ratioofoleictopalmiticacidisadietarydeterminantofthrombogenicandfibrinolyticfactorsduringthepostprandialstateinmen
...ioofoleictopalmiticacid[andthatofmonounsaturatedtosaturatedfattyacids(MUFA:SFA)]inthedietaffectspostprandialconcentrationsoftriacylglycerols,tissuefactor(TF),fibrinogen,tissue-typeplasminogenactivator(t-PA),andplasminogenactivatorinhibitor1(PAI-1).Design:Westudiedtheeffectsofdietsenrichedinoliveoil(...
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不同糖耐量人群血浆脂肪酸谱与胰岛素抵抗
...NGT、IGT和DM组依次升高,差异有显著性;血浆饱和脂肪酸(SFA)从NGT、IGT、DM亚组依次升高;NGT组的多不饱和脂肪酸(PUFA)与SFA的比率高于IGT组和DM组;血浆软脂酸、花生四烯酸、二十二烷酸、SFA与IAI呈负相关;PUFA/SFA与IAI呈正相关。...
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不同糖耐量人群血浆脂肪酸谱与胰岛素抵抗
...NGT、IGT和DM组依次升高,差异有显著性;血浆饱和脂肪酸(SFA)从NGT、IGT、DM亚组依次升高;NGT组的多不饱和脂肪酸(PUFA)与SFA的比率高于IGT组和DM组;血浆软脂酸、花生四烯酸、二十二烷酸、SFA与IAI呈负相关;PUFA/SFA与IAI呈正相关。...
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OSAHS的脂肪积聚,瘦素及高碳酸血症
...在论证脂肪堆积的部位如内脏脂肪积聚和皮下脂肪积聚(SFA)是否会引起肺换气不足,循环瘦素水平是否参与了OSAHS中常见的肺换气不足的发病机理。他们对106名血碳酸正常,79名高碳酸血症的OSAHS患者用腹部CT测量了VFA和SFA,同...
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Macronutrientintakeandglycemiccontrolinapopulation-basedsampleofAmericanIndianswithdiabetes:theStrongHeartStudy
...ely).Nosignificantassociationwasfoundbetweenpolyunsaturatedfattyacidsortransfattyacidsandglycemiccontrolinthispopulation.Conclusions:ThesedatasuggestthatahigherconsumptionoftotalfatandsaturatedandmonounsaturatedfattyacidsandalowerintakeofcarbohydratesareassociatedwithpoorglycemiccontrolindiabeticAme...
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外周动脉病的目前治疗方法---导管介入(2)
...者中,闭塞比狭窄更常见。二大技术进展方便了股浅动脉(SFA)闭塞的治疗,甚至(10cm)长段或慢性闭塞也有可能再通。第1是使用了亲水性导丝。第二是使用溶栓治疗,这一方法已证明有效,甚至用于一些慢性完全闭塞的患者,因为下肢动...
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Polymorphismexon1variantatthelocusofthescavengerreceptorclassBtypeIgene:influenceonplasmaLDLcholesterolinhealthysubjectsduringthecon
.../2)].Bothgroupsconsumed3dietslasting4wkeach.Thefirstwasasaturatedfattyacid(SFA)richdiet(38%fat,20%SFA),whichwasfollowedbyacarbohydrate(Cho)richdiet(30%fat,10%SFA,55%carbohydrate)oramonounsaturatedfattyacid(MUFA),oliveoilrichdiet(38%fat,22%MUFA)accordingtoarandomizedcrossoverdesign....
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TCT2006试验荟萃(三)
...架柱的药物浓度最高,而此处的愈合也是最重要的问题。SFA:支架断裂?SIROCCO(热风)?非植入性的局部药物分布不需要持续性释放。因此,我们不禁要问:是否需要持续的药物释放?第一个研究:IopromidePaclitaxe,(JACC,2003;42:1415-...
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外周动脉病经皮介入治疗进展
...或闭塞在经血管造影考虑血运重建的患者中,股浅动脉(SFA)与腘动脉闭塞比狭窄更常见。下肢动脉闭塞典型特征为长段凝胶样血栓附及在高度粥样硬化的病变上。由于介入技术的进展方便了股浅动脉(SFA)闭塞的治疗,甚至长段(...
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铁蛋白可以提示全身脂肪含量
...查了248名日本受试者的内脏脂肪区(VFA)和皮下脂肪区(SFA),其中140人患有2型糖尿病,其他人健康状况良好。为了排除结果受脂肪肝影响的可能性,研究没有招募既往有大量饮酒史的受试者。根据研究结果,科学家们发现血...
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糖调节异常患者血中游离脂肪酸水平与动脉粥样硬化的关系
...率。结果(1)与NGT组比较,IGR和T2DM组血清FFA和饱和脂肪酸(SFA)水平明显升高(P<0.05);(2)多不饱和脂肪酸(PUSFA)水平降低(P<0.01);IMT增厚,动脉斑块的发病率增高(P<0.05);(3)IMT厚度与血清SFA水平呈正相关,与PUSFA水平呈负相关。可见...
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Differencesinglucose-dependentinsulinotrophicpolypeptidehormoneandhepaticlipaseinsubjectsofsouthernandnorthernEurope:implicationsforpostpran
...testmealsofidenticalmacronutrientcompositionbutdifferentsaturatedfattyacid(SFA)andmonounsaturatedfattyacid(MUFA)contentsonpostprandialGIP,insulin,theratioofincrementaltriacylglyceroltoapolipoproteinB-48(amarkerofchylomicronsize),andtheactivityofpostheparinlipases.Results:FastingandpostprandialGIPcon...
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Contributionofpostprandiallipemiatothedietaryfat-mediatedchangesinendogenouslipoprotein-cholesterolconcentrationsinhumans
...l-richlipoproteins(TRLs).Objective:Wehypothesizedthatthesaturatedfattyacid(SFA)mediatedincreaseandthepolyunsaturatedfattyacid(PUFA)mediateddecreaseinendogenouslipoproteincholesterolarepromotedbypostprandialTRLs.Design:Weperformeda16-dcrossoverdietstudytoexaminetheeffectofPUFA-rich[ratioo...
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MacrophagecholesteroleffluxelicitedbyhumantotalplasmaandbyHDLsubfractionsisnotaffectedbydifferenttypesofdietaryfattyacids
...calorieintakebeintheformoffat,wecomparedtheresultsoftheintakeof30%ofenergyasfatindietsenrichedwithtrans,polyunsaturated,orsaturatedFAs.ThesedietaryeffectsonthecompositionandabilityofHDL2,HDL3,andtotalplasmatoeffluxcholesterolfrommouseperitonealmacrophagesthatpreviouslywereloadedwithLDL-acetylated14C...
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ApolipoproteinEgenepromoter219GTpolymorphismincreasesLDL-cholesterolconcentrationsandsusceptibilitytooxidationinresponsetoadietrichin
...0TT)completed3dietaryperiods,eachlasting4wk.Thefirstwasasaturatedfattyacid(SFA)-richdiet[38%fat20%SFAand12%monounsaturatedfattyacid(MUFA)and47%carbohydrates(CHO)],whichwasfollowedbyaCHO-richdiet(30%fat10%SFAand12%MUFAand55%CHO)oraMUFA-richdiet(38%fat10%SFAand22%MUFA...
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ExtendedVirulenceGenotypesandPhylogeneticBackgroundofEscherichiacoliIsolatesfromPatientswithCystitis,Pyelonephritis,orProstatitis
...rofuniqueVFsdetected,withadjustmentformultipledetectionofthepap(Pfimbriae),sfa/foc(S/F1Cfimbriae),andkpsII(group2capsule)operons.TheE.coliphylogeneticgroupoforigin(A,B1,B2,orD),asinitiallydefinedonthebasisofmultilocusenzymeelectrophoresis[15],wasdeterminedbyuseofa3-locusPCR-basedmethod[12].Eachisola...
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Flow-MediatedDilatationIsImpairedbyaHigh–SaturatedFatDietbutNotbyaHigh-CarbohydrateDiet
...drate(CARB)dietimpairedendothelialvasodilationcomparedwithhighsaturatedfat(SFA),monounsaturatedfat(MUFA),orpolyunsaturatedfat(PUFA)diets.MethodsandResults—Fortyhealthysubjectswererandomlycrossedoverto4,3-weekisocaloricdietshighinPUFA,MUFA,orSFA,containingatleast25goftherelevantfatoralow-fat,CARB,h...
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四、近交系动物在免疫研究中的应用
...途径。 Katz过去证明在小鼠中有变态反应抑制因子(SFA)可抑制小鼠IgE的应答。在此次讨论中它以大量的实验证据证实了人SFA的存在。SFA能选择性地抑制IgE抗体合成。人SFA来自双向混合淋巴细胞培养(MLR)的上清液。测定系...
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Plasmafattyacidcompositionisassociatedwiththemetabolicsyndromeandlow-gradeinflammationinoverweightadolescents
...aredwithoverweightadolescents,normal-weightadolescentshadlowersaturatedFAs(SFAs)inbothphospholipids(P0.001)andCEs(P0.01)andhigherdocosahexaenoicacidinphospholipids(P0.001).Inoverweightsubjects,FAcompositionwasassociatedwithMSfeaturesindependentofbodyfat.TheoddsratiosofMSfora0.1increaseintheratioofpo...
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Carbohydraterestrictioniseffectiveinimprovingatherogenicdyslipidemiaevenintheabsenceofweightloss
...thesubjectsreceivingagreaterpercentage(15%)ofenergyfromsaturatedfattyacids(SFA).Thenegativeconclusionstandsinstarkcontrasttothedatainthepaperthatshowthatcarbohydraterestrictioniseffectiveforimprovingatherogenicdyslipidemiaevenintheabsenceofweightloss.Thereasonmostmarkerswerelessresponsivetoweightlos...
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候鸟在葡萄酒酿造中起着重要的作用
...349只候鸟,然后将他们分类标记,并测量了皮下脂肪量(SFA)。然后采用基因方法分析酵母种类。 结果 在32.66%的候鸟身上发现了野生酵母。在鹟科、鸫科、雀科这三种鸟类身上的酵母量最大。 通过基因分析共找到了125...
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DietarycholesteroldoesnotincreasebiomarkersforchronicdiseaseinapediatricpopulationfromnorthernMexico
...(20).Viewthistable:TABLE2.Intakesofcarbohydrate;protein;totalfat;saturated(SFA),polyunsaturated(PUFA),andmonounsaturated(MUFA)fattyacids;dietarycholesterol;dietaryfiber;andvitaminEofhyper-andhyporespondersduringtheEGGandSUBperiods1Inregardtoresponseclassification,theamountoftotalcaloriesconsumedwasn...
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Fattyacidcompositionofskeletalmusclereflectsdietaryfatcompositioninhumans
...andomlyassignedtodietscontainingahighproportionofeithersaturatedfattyacids(SFAs)[totalfat,36%ofenergy;SFAs,18%ofenergy;monounsaturatedfattyacids(MUFAs),10%ofenergy]orMUFAs(totalfat,35%ofenergy;SFAs,9%ofenergy;MUFAs,19%ofenergy)for3mo.Withineachdietgroup,therewasasecondrandomassignmenttosupplementati...
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Dietarycis-monounsaturatedfattyacidsandmetaboliccontrolintype2diabetes
...ctiveoffattyacidcomposition.LimitedexperimentalevidencesuggeststhatMUFAdietsfavorablyinfluencebloodpressure,coagulation,endothelialactivation,inflammation,andthermogeniccapacity.Energy-controlledhigh-MUFAdietsdonotpromoteweightgainandaremoreacceptablethanlow-fatdietsforweightlossinobesesubjects.Thus...
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ReplytoPMarckmann
...;5.Kris-EthertonPM,fortheDELTAinvestigators.Effectsofreplacingsaturatedfat(SFA)withmonounsaturatedfat(MUFA)orcarbohydrate(CHO)onplasmalipidsandlipoproteinsinindividualswithmarkersforinsulinresistance.FASEBJ1996;10:2666.Yu-PothS,ZhaoG,EthertonT,NaglakM,JonnalagaddaS,Kris-EthertonPM.EffectsoftheNation...
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Dietaryandplasmalipid,lipoprotein,andapolipoproteinprofilesamongelderlyHispanicsandnon-Hispanicsandtheirassociationwithdiabetes
...nergyintakefromtotalcarbohydrates,totalfat[monounsaturated(MUFA),saturated(SFA),andpolyunsaturated(PUFA)fattyacids],andalcohol.Cholesterol(mg)intakewasalsoevaluated.Aphysicalactivityscorewascalculatedbymultiplyingthetimespentindifferentactivitiesbycorrespondingweightingfactorsthatparalleltheincrease...
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Fattyacidsaturationofthedietandplasmalipidconcentrations,lipoproteinparticleconcentrations,andcholesteroleffluxcapacity
...teenwomenand24menfollowedinthesamesequence4dietscontaining35%oftotalenergyasfat.Thesaturatedfatdietcontained17%palmoil;themonounsaturatedfatdiet,20.9%oliveoil;then-6polyunsaturatedfatdiet,12.5%sunfloweroil;andthen-3polyunsaturatedfatdiet,sunfloweroilsupplementedwith44.5gfishoil/d.Eachphaselast...
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游离脂肪酸在高血压伴代谢综合征的发病机制中的作用探讨
...的能源物质之一。FFA又可分为饱和脂肪酸(saturatedfattyacid,SFA)、单不饱和脂肪酸(monounsaturatedfattyacid,MuFA)和多不饱和脂肪酸(polyunsaturatedfattyacid,PuFA)。TangY[1]等的研究发现,磷酸二酯酶3B基因(phosphodiesterase3B,PDE3B)在脂肪组织表...
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Dietaryfatandplasmatotalhomocysteineconcentrationsin2adultagegroups:theHordalandHomocysteineStudy
...esandmeasurementofplasmatHcyconcentrations.Results:TheintakeofsaturatedFAs(SFAs)waspositivelyandsignificantly(Pfortrend0.001)associatedwithtHcyconcentrations;thedifferenceinplasmatHcyconcentrationsbetweenthehighestandlowestquartilesofSFAswas8.8%.Theintakeofmarinevery-long-chainn3FAswasinversel...
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TheAla54Thrpolymorphismofthefattyacidbindingprotein2geneisassociatedwithachangeininsulinsensitivityafterachangeinthetypeofdieta
...4wk.Thefirstdiet,whichallsubjectsconsumed,wasahighsaturatedfattyacid(SFA)diet(38%ofenergyasfatand20%ofenergyasSFAs).Thesecondandthirddietswereadministeredaccordingtoarandomizedcrossoverdesign,andtheyconsistedofalow-fatandhigh-carbohydratediet(CHOdiet;28%ofenergyfromfatand10%ofenergyfromSFAs)an...